SCHEMBL3365807

SCHEMBL3365807

CC1(C)C(C=C(Cl)C(F)(F)F)C1OC(=O)Cl

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11203300 0.89 MEN1 (0.34) MEN1KMT2ATDP1
SCHEMBL9518733 0.89 MEN1 (0.42) MEN1KMT2ATDP1
SCHEMBL11197055 0.83 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL10828081 0.82 HPGD (0.34) MEN1KMT2ATDP1
SCHEMBL10483036 0.82 HPGD (0.34) MEN1KMT2ATDP1
SCHEMBL10832189 0.82 HPGD (0.34) MEN1KMT2ATDP1
SCHEMBL11492765 0.81 MEN1 (0.41) MEN1KMT2ATDP1
SCHEMBL8027463 0.81 MEN1 (0.41) MEN1KMT2ATDP1
SCHEMBL3367420 0.81 MEN1 (0.41) MEN1KMT2ATDP1
SCHEMBL7603511 0.81 MEN1 (0.41) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1578720-B2 PRODUCTION PROCESS OF GAMMA-CYHALOTHRIN SYNGENTA LTD (GB) 2016-08-31 EP disclosed
EP-1578720-B1 PRODUCTION PROCESS OF GAMMA-CYHALOTHRIN SYNGENTA LTD (GB) 2013-05-15 EP disclosed
EP-1303474-B1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE PYRETHROID INSECTICIDES SYNGENTA LTD (GB) 2010-10-06 EP disclosed
US-7507852-B2 Chlorinating 1R cis-Z 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cyclopropanecarboxylic acid to give 1R cis-Z 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cyclopropanecarboxylic acid chloride; esterifying with the (S)-cyanohydrin of 3-phenoxy benzaldehyde SYNGENTA LIMITED (GB) 2009-03-24 US disclosed
US-7468453-B2 Production process of gamma-cyhalothrin SYNGENTA LIMITED (GB) 2008-12-23 US disclosed
EP-1599442-B1 PROCESS FOR PREPARING GAMMA-CYHALOTHRIN SYNGENTA LTD (GB) 2007-08-08 EP disclosed
US-20060148892-A1 Process for preparing gamma-cyhalothrin SYNGENTA LIMITED (GB) 2006-07-06 US disclosed
US-20060100457-A1 Production process of gamma-cyhalothrin SYNGENTA LIMITED (GB) 2006-05-11 US disclosed
EP-1599442-A1 PROCESS FOR PREPARING GAMMA-CYHALOTHRIN Syngenta Limited (GB) 2005-11-30 EP disclosed
US-6875885-B2 Process for the preparation of enantiomerically pure pyrethroid insecticides SYNGENTA LIMITED (GB) 2005-04-05 US disclosed
WO-2004074237-A1 PROCESS FOR PRPARING GAMMA-CYHALOTHRIN SYNGENTA LIMITED (GB) 2004-09-02 WO disclosed
US-20030199709-A1 Process for the preparation of enantiomerically pure pyrethroid insecticides SYNGENTA LIMITED (GB) 2003-10-23 US disclosed
WO-2003053905-A1 A PROCESS FOR THE PRODUCTION OF 1R PYRETHROID ESTERS SYNGENTA LIMITED (GB) 2003-07-03 WO disclosed
EP-1303474-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE PYRETHROID INSECTICIDES Syngenta Limited (GB) 2003-04-23 EP disclosed
WO-2002006202-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE PYRETHROID INSECTICIDES SYNGENTA LIMITED (GB) 2002-01-24 WO disclosed
EP-0414059-B1 Dihalogenovinylbenzylesters, process and starting material for their preparation and their utilization for the control of parasites BASF AG (DE) 1993-10-27 EP disclosed
EP-0347694-B1 PYRETHROIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING PESTS BASF Aktiengesellschaft (DE) 1992-08-26 EP disclosed
EP-0414059-A1 Dihalogenovinylbenzylesters, process and starting material for their preparation and their utilization for the control of parasites BASF Aktiengesellschaft (DE) 1991-02-27 EP disclosed
EP-0347694-A1 Pyrethroids, process for their preparation and their use in combating pests BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
EP-0242778-A1 Separation of diastereo isomers BAYER AG (DE) 1987-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100457-A1 Production process of gamma-cyhalothrin CBR3, CBR1, POR MEN1 3919/4885KMT2A 4331/4885TDP1 4430/4885
US-20060148892-A1 Process for preparing gamma-cyhalothrin DHCR24, CBR1, CBR3 MEN1 3053/4885KMT2A 2319/4885TDP1 4760/4885
US-20030199709-A1 Process for the preparation of enantiomerically pure pyrethroid insecticides CYP4B1, CYP4A11, DDT MEN1 3522/4885KMT2A 1556/4885TDP1 3111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.