Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027463 | 1.00 | MEN1 (0.41) | MEN1KMT2ATDP1 | |
| SCHEMBL11492765 | 1.00 | MEN1 (0.41) | MEN1KMT2ATDP1 | |
| SCHEMBL7173074 | 1.00 | MEN1 (0.41) | MEN1KMT2ATDP1 | |
| SCHEMBL3367420 | 1.00 | MEN1 (0.41) | MEN1KMT2ATDP1 | |
| SCHEMBL9516767 | 0.85 | MEN1 (0.32) | MEN1KMT2ATDP1 | |
| SCHEMBL10828119 | 0.83 | HPGD (0.31) | — | |
| SCHEMBL3038976 | 0.83 | HPGD (0.31) | — | |
| SCHEMBL7174560 | 0.83 | HPGD (0.31) | — | |
| SCHEMBL10828326 | 0.83 | HPGD (0.31) | — | |
| SCHEMBL8995504 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855446-A | Process for the resolution of racemates using lactone esters | THE SHERWIN WILLIAMS COMPANY (US) | 1989-08-08 | — | — | US | claimed |
| EP-0060445-B1 | PROCESS FOR THE RESOLUTION OF RACEMATES AND LACTONE ESTERS USED IN SAID PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-08-01 | — | — | EP | claimed |
| EP-0060445-A1 | Process for the resolution of racemates and lactone esters used in said process | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-09-22 | — | — | EP | claimed |
| US-20020161244-A1 | Preparation of cis-6,6-dimethyl-3-oxa-bicyclo(3.1.0)hexan-2-one | LEVIN DANIEL (GB) | 2002-10-31 | — | — | US | disclosed |
| US-6414165-B1 | REACTING LOWER ALKYL ESTER OF 4,5-EPOXY-3,3-DIMETHYLPENTANOIC ACID OR SULFONIC ESTER OF BETA,BETA-DIMETHYL-GAMMA-(HYDROXYMETHYL)-GAMMA-BUTYROLACTONE WITH ALKALI METAL OR QUATERNARY AMMONIUM ALKOXIDE IN ETHER | SYNGENTA LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |
| EP-0842137-B1 | A PROCESS FOR THE PREPARATION OF CYCLOPROPANE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR | CHEMINOVA AGRO AS (DK) | 2000-04-05 | — | — | EP | disclosed |
| US-5986130-A | REACTION OF HYDROXYTETRAHYDROFURANONE AND HALOFLUORINATED ETHANE IN THE PRESENCE OF ZINC | CHEMINOVA AGRO A/S (DK) | 1999-11-16 | — | — | US | disclosed |
| EP-0793637-B1 | HALOGENATED ESTERS USEFUL AS INTERMEDIATES FOR INSECTICIDES | ZENECA LTD (GB) | 1998-10-28 | — | — | EP | disclosed |
| US-5756835-A | Halogenated esters useful as intermediates for insecticides | ZENECA LIMITED (GB) | 1998-05-26 | — | — | US | disclosed |
| US-5750769-A | Halogenated esters useful as intermediates for insecticides | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| EP-0264457-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLIC ACIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-31 | — | — | EP | disclosed |
| EP-0303636-B1 | A PROCESS FOR THE PREPARATION OF PYRETHROID TYPE ESTER COMPOUNDS | LUCKY, LTD. (KR) | 1992-05-13 | — | — | EP | disclosed |
| US-4874887-A | ONE STEP CONDENSATION OF ORGANIC ACID, ALDEHYDE, WATER SOLUBLE CYANIDE USING PHASE TRANSFER CATALYST, INORGANIC BASE, SULFONYL COMPOUND | LUCKY, LTD. (KR) | 1989-10-17 | — | — | US | disclosed |
| US-4855446-A | Process for the resolution of racemates using lactone esters | THE SHERWIN WILLIAMS COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0303636-A1 | A PROCESS FOR THE PREPARATION OF PYRETHROID TYPE ESTER COMPOUNDS. | LUCKY LTD (KR) | 1989-02-22 | — | — | EP | disclosed |
| WO-1988006151-A1 | A PROCESS FOR THE PREPARATION OF PYRETHROID TYPE ESTER COMPOUNDS | LUCKY, LTD. (KR) | 1988-08-25 | — | — | WO | disclosed |
| EP-0264457-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLIC ACIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-04-27 | — | — | EP | disclosed |
| US-4501908-A | 2,3-Isopropylidene ribonic acid, 1,4-lactones | HOFFMANN-LA ROCHE INC. (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0060445-B1 | PROCESS FOR THE RESOLUTION OF RACEMATES AND LACTONE ESTERS USED IN SAID PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-08-01 | — | — | EP | disclosed |
| EP-0060445-A1 | Process for the resolution of racemates and lactone esters used in said process | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161244-A1 | Preparation of cis-6,6-dimethyl-3-oxa-bicyclo(3.1.0)hexan-2-one | MSMO1, CYP2B6, CYP2D6 | MEN1 966/4885KMT2A 2743/4885TDP1 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.