Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.87 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 5/20 | 0.49 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1275281 | 1.00 | ATM (0.87) | ATMHCAR2MAPTRAB9ANPSR1 | |
| Acetic Acid SCHEMBL1275284 | 1.00 | ATM (0.87) | ATMHCAR2MAPTRAB9ANPSR1 | |
| Butyl Fumarate SCHEMBL971541 | 0.94 | HCAR2 (0.92) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL269917 | 0.93 | ATM (1.00) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL41998 | 0.93 | ATM (1.00) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL28154 | 0.93 | ATM (1.00) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL28153 | 0.93 | ATM (1.00) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL10423863 | 0.93 | ATM (1.00) | ATMHCAR2MAPTRAB9ANPSR1 | |
| Acetic Acid SCHEMBL10955726 | 0.92 | HCAR2 (0.82) | ATMHCAR2MAPTRAB9ANPSR1 | |
| Acetic Acid SCHEMBL22443287 | 0.92 | HCAR2 (0.82) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257673-A1 | Laminates, their production and use | CELANESE EMULSIONS GMBH (DE) | 2006-11-16 | — | — | US | claimed |
| US-20050124759-A1 | Aqueous coating compositions method for the production thereof and their use for producing in particular thixotropic coating compositions | CELANESE EMULSIONS GMBH (DE) | 2005-06-09 | — | — | US | claimed |
| US-8436088-B2 | Plasters and renders and paints, copolymer dispersions and their use | CELANESE EMULSIONS GMBH (DE) | 2013-05-07 | — | — | US | disclosed |
| US-20100144925-A1 | Plasters and Renders and Paints, Copolymer Dispersions and Their Use | NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) | 2010-06-10 | — | — | US | disclosed |
| US-7491777-B2 | Polymer dispersions having improved water-vapor barrier action, their production and use for food coating | CELANESE EMULSIONS GMBH (DE) | 2009-02-17 | — | — | US | disclosed |
| US-20060257673-A1 | Laminates, their production and use | CELANESE EMULSIONS GMBH (DE) | 2006-11-16 | — | — | US | disclosed |
| US-20050154123-A1 | Polymer dispersions having improved water-vapor barrier action, their production and use for food coating | CELANESE EMULSIONS GMBH (DE) | 2005-07-14 | — | — | US | disclosed |
| CN-1629201-A | Polymer dispersions with improved water-vapour barrier properties, their preparation and use in food coating | CELANESE EMULSIONS GMBH (DE) | 2005-06-22 | — | — | CN | disclosed |
| US-20050124759-A1 | Aqueous coating compositions method for the production thereof and their use for producing in particular thixotropic coating compositions | CELANESE EMULSIONS GMBH (DE) | 2005-06-09 | — | — | US | disclosed |
| US-5173432-A | Apparatus and method for measuring the concentration or partial pressure of oxygen | THE DOW CHEMICAL COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| US-4994396-A | Method for measuring the concentration or partial pressure of oxygen | THE DOW CHEMICAL COMPANY (US) | 1991-02-19 | — | — | US | disclosed |