Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | LHCGR | P22888 | 12/20 | 0.63 |
| ▸ | HHAT | Q5VTY9 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2305817 | 0.89 | MAPK1 (0.64) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL3365428 | 0.88 | LHCGR (0.63) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2311877 | 0.86 | MAPK1 (0.60) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2307799 | 0.85 | LHCGR (0.74) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2304864 | 0.85 | MAPK1 (0.62) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL7888237 | 0.85 | MAPK1 (0.67) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2312117 | 0.83 | MAPK1 (0.57) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2307689 | 0.82 | LHCGR (0.56) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL15278800 | 0.82 | MAPK1 (0.67) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2311671 | 0.81 | MEN1 (0.54) | MAPK1NPSR1LHCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | GRUENENTHAL GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | KCNQ1, KCNQ3, KCNQ2 | MAPK1 1262/4885NPSR1 1084/4885LHCGR 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.