Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.55 |
| ▸ | GNB1 | P62873 | 5/20 | 0.55 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.50 |
| ▸ | P2RY4 | P51582 | 8/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CHAT | P28329 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366866 | 1.00 | GNG2 (0.55) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL3364414 | 0.89 | GNG2 (0.56) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL3364421 | 0.89 | GNG2 (0.56) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL3363896 | 0.81 | GNG2 (0.82) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL3025546 | 0.80 | GNG2 (0.80) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL13021512 | 0.74 | GNG2 (0.92) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL3363102 | 0.72 | HIF1A (0.52) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL3363100 | 0.72 | HIF1A (0.52) | GNG2GNB1PHLPP2P2RY4CYP1A2 | |
| SCHEMBL3363854 | 0.72 | POLB (0.50) | CYP1A2CYP2C9HSD17B10ALDH1A1HPGD | |
| SCHEMBL13496253 | 0.72 | POLB (0.50) | CYP1A2CYP2C9HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100031452-A1 | AZO DYES | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2010-02-11 | — | — | US | disclosed |
| WO-2010003969-A2 | NEW AZO DYES | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100031452-A1 | AZO DYES | IK, H1-10, RB1 | GNG2 2036/4885GNB1 682/4885PHLPP2 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.