Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 7/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366983 | 1.00 | OXTR (0.56) | OXTRAVPR1AMAPTLMNAAVPR2 | |
| SCHEMBL3366259 | 0.87 | OXTR (0.49) | OXTRAVPR1AMAPTLMNAMEN1 | |
| SCHEMBL3366261 | 0.87 | OXTR (0.49) | OXTRAVPR1AMAPTLMNAMEN1 | |
| SCHEMBL3366525 | 0.86 | OXTR (0.73) | OXTRAVPR1AMAPTLMNAAVPR2 | |
| SCHEMBL3366530 | 0.86 | OXTR (0.73) | OXTRAVPR1AMAPTLMNAAVPR2 | |
| SCHEMBL14349072 | 0.84 | OXTR (0.59) | OXTRAVPR1AMAPTLMNAAVPR2 | |
| SCHEMBL3366598 | 0.84 | OXTR (0.59) | OXTRAVPR1AMAPTLMNAAVPR2 | |
| SCHEMBL3367849 | 0.84 | OXTR (0.59) | OXTRAVPR1AMAPTLMNAAVPR2 | |
| SCHEMBL3365652 | 0.82 | OXTR (0.51) | OXTRAVPR1AMAPTLMNAMEN1 | |
| SCHEMBL3365656 | 0.82 | OXTR (0.51) | OXTRAVPR1AMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | claimed |