Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137140 | 0.85 | NPC1 (0.50) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL29137138 | 0.85 | NPC1 (0.50) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL29137125 | 0.85 | NPC1 (0.50) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL29137159 | 0.85 | NPC1 (0.50) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL29137120 | 0.85 | NPC1 (0.50) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL9346505 | 0.84 | ICMT (0.47) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL29137146 | 0.83 | NPC1 (0.47) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL11124165 | 0.80 | MAPT (0.40) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL27966901 | 0.78 | TDP1 (0.42) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25227148 | 0.78 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623798-B2 | Lubricating oil compositions containing a tetraalkyl-napthalene-1,8 diamine antioxidant | CHEVRON ORONITE COMPANY LLC (US) | 2014-01-07 | — | — | US | disclosed |
| EP-2077315-B1 | Lubricating oil compositions containing a tetraalkyl-napthalene-1,8 diamine antioxidant and a diarylamine antioxidant | CHEVRON ORONITE CO (US) | 2012-10-31 | — | — | EP | disclosed |
| US-20100152079-A1 | LUBRICATING OIL COMPOSITIONS CONTAINING A TETRAALKYL-NAPTHALENE-1,8 DIAMINE ANTIOXIDANT | CHEVRON ORONITE COMPANY LLC | 2010-06-17 | — | — | US | disclosed |
| EP-2077315-A1 | Lubricating oil compositions containing a tetraalkyl-napthalene-1,8 diamine antioxidant | Chevron Oronite Company LLC (US) | 2009-07-08 | — | — | EP | disclosed |