Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | CETP | P11597 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389180 | 0.86 | TSHR (0.63) | TSHRCETPALDH1A1FOLH1IDO1 | |
| SCHEMBL10200001 | 0.84 | TSHR (0.55) | TSHRCETPALDH1A1FOLH1IDO1 | |
| SCHEMBL12746424 | 0.83 | TSHR (0.59) | TSHRCETPALDH1A1FOLH1IDO1 | |
| SCHEMBL6825537 | 0.83 | TSHR (0.70) | TSHRCETPALDH1A1FOLH1SRC | |
| SCHEMBL10308513 | 0.83 | TSHR (0.59) | TSHRCETPALDH1A1FOLH1IDO1 | |
| SCHEMBL206609 | 0.81 | TSHR (0.68) | TSHRCETPALDH1A1IDO1SRC | |
| SCHEMBL8038494 | 0.81 | TSHR (0.57) | TSHRCETPALDH1A1FOLH1IDO1 | |
| SCHEMBL14812949 | 0.81 | TSHR (0.57) | TSHRCETPALDH1A1FOLH1IDO1 | |
| SCHEMBL12567320 | 0.81 | TSHR (0.57) | TSHRCETPALDH1A1FOLH1IDO1 | |
| SCHEMBL8619121 | 0.81 | TSHR (0.57) | TSHRCETPALDH1A1FOLH1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056795-A1 | NOVEL SYNTHETIC DINUCLEOSIDE POLYPHOSPHATE ANALOGS AND THEIR USE AS NEW THERAPEUTIC AND/OR DIAGNOSTIC MODALITIES | ZATA PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| CN-1014321-B | PROCESS FOR PRODUCING GLUTACONIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1991-10-16 | — | — | CN | disclosed |
| CN-85106433-A | Produce the method for glutaconic acid derivative | — | 1987-03-18 | — | — | CN | disclosed |