SCHEMBL8619121

SCHEMBL8619121

COP(C)(=O)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
CETP P11597 3/20 0.47
PKM P14618 1/20 0.43
ALDH1A1 P00352 2/20 0.42
LAP3 P28838 1/20 0.42
FOLH1 Q04609 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SRC P12931 1/20 0.41
IDO1 P14902 1/20 0.40
MAOB P27338 1/20 0.40
PDPK1 O15530 1/20 0.40
MTOR P42345 1/20 0.40
ALPG P10696 1/20 0.40
PTK2B Q14289 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL389180 0.90 TSHR (0.63) TSHRCETPPKMALDH1A1FOLH1
SCHEMBL17034260 0.82 TSHR (0.55) TSHRCETPPKMALDH1A1
SCHEMBL12313535 0.82 TSHR (0.55) TSHRCETPPKMALDH1A1FOLH1
SCHEMBL991032 0.82 TSHR (0.59) TSHRCETPALDH1A1LAP3FOLH1
SCHEMBL6423059 0.82 TSHR (0.59) TSHRCETPALDH1A1LAP3FOLH1
SCHEMBL3367142 0.81 TSHR (0.63) TSHRCETPPKMALDH1A1FOLH1
SCHEMBL8397806 0.81 PKM (0.49) TSHRPKMALDH1A1LAP3IDO1
SCHEMBL26569501 0.81 TSHR (0.53) TSHRCETPPKMLAP3SRC
SCHEMBL19986359 0.81 TSHR (0.53) TSHRCETPPKMALDH1A1FOLH1
SCHEMBL28822078 0.80 TSHR (0.57) TSHRCETPALDH1A1LAP3FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118198513-A Sodium ion battery and preparation method and application thereof 溧阳中科海钠科技有限责任公司 2024-06-14 CN claimed
CN-113089330-B Polyester durable flame retardant and preparation method and application thereof 苏州联胜化学有限公司 2022-10-25 CN claimed
CN-113089330-A Polyester durable flame retardant and preparation method and application thereof 苏州联胜化学有限公司 2021-07-09 CN claimed
US-20230045939-A1 STABLE VACCINE AGAINST CLOSTRIDIUM DIFFICILE IDORSIA PHARMACEUTICALS LTD (CH) 2023-02-16 US disclosed
CN-113089330-B Polyester durable flame retardant and preparation method and application thereof 苏州联胜化学有限公司 2022-10-25 CN disclosed
CN-113089330-B Polyester durable flame retardant and preparation method and application thereof 苏州联胜化学有限公司 2022-10-25 CN disclosed
CN-114300749-A Wide-temperature flame-retardant lithium ion battery electrolyte 江苏卫蓝新能源电池有限公司 2022-04-08 CN disclosed
CN-113089330-A Polyester durable flame retardant and preparation method and application thereof 苏州联胜化学有限公司 2021-07-09 CN disclosed
CN-113089330-A Polyester durable flame retardant and preparation method and application thereof 苏州联胜化学有限公司 2021-07-09 CN disclosed
CN-107078352-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2020-04-28 CN disclosed
CN-105969249-A Encapsulating glue film for N type two-sided batteries 常州斯威克光伏新材料有限公司 2016-09-28 CN disclosed
EP-0501543-B1 Process for the production of polyesters with increased electroconductivity AGFA GEVAERT NV (BE) 1998-05-20 EP disclosed
WO-1996000733-A1 DIPHOSPHATE OR TRIPHOSPHATE NON-HYDROLYSABLE STABLE ANALOGUES AND METHODS FOR THEIR PREPARATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1996-01-11 WO disclosed
US-5254288-A Adding a metallic salt in ethylene glycol solution to the reaction mixture in such manner that it cannot escape AGFA-GEVAERT, N.V. (BE) 1993-10-19 US disclosed
EP-0501543-A1 Process for the production of polyesters with increased electroconductivity AGFA-GEVAERT N.V. (BE) 1992-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230045939-A1 STABLE VACCINE AGAINST CLOSTRIDIUM DIFFICILE DDOST, SI, CD4 TSHR 3529/4885CETP 1110/4885PKM 1928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.