Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | CYCS | P99999 | 4/20 | 0.36 |
| ▸ | TOP1 | P11387 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337060 | 0.91 | STAT3 (0.40) | STAT3STAT1CYCSTOP1MEN1 | |
| SCHEMBL336231 | 0.90 | STAT3 (0.43) | STAT3STAT1CYCSTOP1MEN1 | |
| SCHEMBL336654 | 0.87 | STAT3 (0.43) | STAT3STAT1CYCSTOP1ABCG2 | |
| SCHEMBL336614 | 0.77 | STAT3 (0.36) | STAT3STAT1CYCSTOP1ABCG2 | |
| SCHEMBL336446 | 0.77 | STAT3 (0.39) | STAT3STAT1CYCSTOP1ABCG2 | |
| SCHEMBL335851 | 0.77 | STAT3 (0.42) | STAT3STAT1CYCSTOP1ABCG2 | |
| SCHEMBL336440 | 0.75 | STAT3 (0.46) | STAT3STAT1CYCSTOP1ABCG2 | |
| SCHEMBL3794157 | 0.74 | TOP1 (0.61) | CYCSTOP1MEN1KMT2APDE2A | |
| SCHEMBL29558419 | 0.74 | TOP1 (0.61) | CYCSTOP1MEN1KMT2APDE2A | |
| SCHEMBL336271 | 0.71 | STAT3 (0.43) | STAT3STAT1CYCSTOP1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140106367-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-04-17 | — | — | US | disclosed |
| US-8530459-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-09-10 | — | — | US | disclosed |
| US-20120082621-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-05 | — | — | US | disclosed |
| US-8097609-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-17 | — | — | US | disclosed |
| US-20090297456-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-03 | — | — | US | disclosed |
| WO-2007047925-A2 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082621-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | ALK, ACVRL1, ACVR1 | STAT3 2034/4885STAT1 2300/4885CYCS 3003/4885 |
| US-20090297456-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | ALK, ACVRL1, ACVR1 | STAT3 1926/4885STAT1 2247/4885CYCS 3035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.