Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 17/20 | 0.55 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369471 | 0.87 | HCRTR1 (0.54) | HCRTR1HCRTR2RAB9ANPC1 | |
| SCHEMBL3369395 | 0.86 | HCRTR1 (0.56) | HCRTR1HCRTR2RAB9ANPC1 | |
| SCHEMBL3368893 | 0.85 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL3366528 | 0.85 | HCRTR1 (0.57) | HCRTR1HCRTR2RAB9ANPC1 | |
| SCHEMBL3366813 | 0.85 | HCRTR1 (0.53) | HCRTR1HCRTR2RAB9ANPC1 | |
| SCHEMBL3366091 | 0.84 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL3369687 | 0.82 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL3367920 | 0.81 | HCRTR1 (0.56) | HCRTR1HCRTR2RAB9ANPC1 | |
| SCHEMBL3366837 | 0.81 | HCRTR1 (0.50) | HCRTR1HCRTR2RAB9ANPC1 | |
| SCHEMBL3367485 | 0.81 | HCRTR1 (0.52) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532141-B1 | 2-PYRROLIDIN-2-YL- [1,3,4]-OXADIAZOLE DERIVATIVES AND THE USE OF THE SAME AS ANTIDEPRESSANTS | GRUENENTHAL GMBH (DE) | 2010-10-13 | — | — | EP | disclosed |