SCHEMBL3367530

SCHEMBL3367530

O=c1c2ccccc2oc2ccc([I+]c3ccccc3)cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.58
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
GLA P06280 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAPT P10636 1/20 0.58
HPGD P15428 1/20 0.58
PGAM1 P18669 1/20 0.58
CASP1 P29466 1/20 0.58
CASP7 P55210 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
HSD17B10 Q99714 1/20 0.58
TTR P02766 2/20 0.56
NPC1 O15118 4/20 0.55
RAB9A P51151 3/20 0.55
POLB P06746 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TBK1 Q9UHD2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3368162 0.95 MAOA (0.64) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL3367571 0.94 MAOA (0.51) MAOAKDM4EALDH1A1GLACYP3A4
Bromide SCHEMBL3371085 0.93 MAOA (0.62) MAOAKDM4EALDH1A1GLACYP3A4
Hydrochloric Acid SCHEMBL3367659 0.93 MAOA (0.62) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL3370825 0.92 TTR (0.49) MAOAKDM4EALDH1A1GLACYP3A4
Acetic Acid SCHEMBL3368203 0.90 NPC1 (0.57) MAOAKDM4EALDH1A1GLACYP3A4
Perchlorate SCHEMBL3369538 0.89 MAOA (0.56) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL3367505 0.89 MAOA (0.56) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL3371463 0.88 MAOA (0.51) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL3370131 0.88 TTR (0.46) MAOAKDM4EALDH1A1GLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1953149-B1 A heterocycle-containing onium salt WAKO PURE CHEM IND LTD (JP) 2010-10-06 EP disclosed
EP-1481973-B1 HETEROCYCLE-BEARING ONIUM SALTS WAKO PURE CHEM IND LTD (JP) 2008-12-31 EP disclosed
EP-1953149-A2 A heterocycle-containing onium salt Wako Pure Chemical Industries, Ltd. (JP) 2008-08-06 EP disclosed