Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrogallol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA1 | P00915 | 2/20 | 0.71 |
| ▸ | EGFR | P00533 | 2/20 | 0.71 |
| ▸ | FYN | P06241 | 2/20 | 0.71 |
| ▸ | MMP9 | P14780 | 2/20 | 0.71 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.71 |
| ▸ | MMP2 | P08253 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CDK2 | P24941 | 1/20 | 0.71 |
| ▸ | MMP12 | P39900 | 1/20 | 0.71 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrogallol SCHEMBL29044406 | 0.91 | ALDH1A1 (0.75) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL20740296 | 0.86 | ALDH1A1 (0.67) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL28732500 | 0.85 | ALDH1A1 (0.75) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL27409245 | 0.84 | ALDH1A1 (0.86) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL27960967 | 0.84 | ALDH1A1 (0.86) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL170157 | 0.84 | ALDH1A1 (1.00) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL3532 | 0.84 | — | — | |
| Catechol SCHEMBL2581350 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL27674772 | 0.81 | ALDH1A1 (0.80) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL16341956 | 0.81 | ALDH1A1 (0.60) | ALDH1A1LMNAHPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303950-B | High-oxygen-content ethanol fuel oil additive and preparation method thereof | 成都新柯力化工科技有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-111303950-A | High-oxygen-content ethanol fuel oil additive and preparation method thereof | 成都新柯力化工科技有限公司 | 2020-06-19 | — | — | CN | claimed |
| CN-104177393-A | Photosensitizer, and preparation method and application thereof | SHENZHEN CHINA RESOURCES GOSUN PHARMACEUTICAL CO LTD | 2014-12-03 | — | — | CN | claimed |
| CN-118600101-B | VTE4 gene for detecting alpha-tocopherol content of sweet corn kernels and application thereof | 广东省农业科学院作物研究所 | 2025-04-01 | — | — | CN | disclosed |
| CN-118726641-B | Shki1 gene mutation site for detecting alpha-tocopherol content of sweet corn kernels and application thereof | 广东省农业科学院作物研究所 | 2025-03-18 | — | — | CN | disclosed |
| CN-118755867-B | Zmhppd gene for detecting gamma-tocotrienol content of sweet corn kernels and application of Zmhppd gene | 广东省农业科学院作物研究所 | 2025-02-07 | — | — | CN | disclosed |
| CN-118755867-A | Zmhppd gene for detecting gamma-tocotrienol content of sweet corn kernels and application of Zmhppd gene | 广东省农业科学院作物研究所 | 2024-10-11 | — | — | CN | disclosed |
| CN-118726641-A | Shki1 gene mutation site for detecting alpha-tocopherol content of sweet corn kernels and application thereof | 广东省农业科学院作物研究所 | 2024-10-01 | — | — | CN | disclosed |
| CN-115838322-B | Polymerization inhibiting composition for olefin compounds and polymerization inhibiting method | 杭州唯铂莱生物科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114304263-B | Thermal processing method for improving carotenoid content of Chinese chestnut | 华南理工大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-115838322-A | Polymerization inhibiting composition for olefin compound and polymerization inhibiting method | 杭州唯铂莱生物科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-2007212-A1 | CASEIN MICELLES FOR NANOENCAPSULATION OF HYDROPHOBIC COMPOUNDS | Technion Research & Development Foundation Ltd. (IL) | 2008-12-31 | — | — | EP | disclosed |
| US-20080127371-A1 | GENES ENCODING 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (HPPD) ENZYMES FOR PLANT METABOLIC ENGINEERING | MOSHIRI FARHAD | 2008-05-29 | — | — | US | disclosed |
| US-7297541-B2 | Genes encoding 4-hydroxyphenylpyruvate dioxygenase (HPPD) enzymes for plant metabolic engineering | MONSANTO TECHNOLOGY LLC (US) | 2007-11-20 | — | — | US | disclosed |
| WO-2007122613-A1 | CASEIN MICELLES FOR NANOENCAPSULATION OF HYDROPHOBIC COMPOUNDS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2007-11-01 | — | — | WO | disclosed |
| EP-1527180-A4 | HOMOGENTISATE PRENYL TRANSFERASE (\"HPT\") NUCLEIC ACIDS AND POLYPEPTIDES, AND USES THEREOF | MONSANTO TECHNOLOGY LLC (US) | 2006-02-15 | — | — | EP | disclosed |
| US-20050289664-A1 | Genes encoding 4-Hydroxyphenylpyruvate dioxygenase (HPPD) enzymes for plant metabolic engineering | MONSANTO TECHNOLOGY, L.L.C. | 2005-12-29 | — | — | US | disclosed |
| EP-1527180-A2 | HOMOGENTISATE PRENYL TRANSFERASE (\"HPT\") NUCLEIC ACIDS AND POLYPEPTIDES, AND USES THEREOF | Monsanto Technology LLC (US) | 2005-05-04 | — | — | EP | disclosed |
| WO-2003080647-A2 | HOMOGENTISATE PRENYL TRANSFERASE ('HPT') NUCLEIC ACIDS AND POLYPEPTIDES, AND USES THEREOF | MONSANTO TECHNOLOGY, LLC (US) | 2003-10-02 | — | — | WO | disclosed |
| US-4368277-A | Porous open-cell filled reactive material | BURINSKY STANISLAV V (SU) | 1983-01-11 | — | — | US | disclosed |