⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197556 | 0.69 | — | — | |
| SCHEMBL1722571 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL16013782 | 0.67 | — | — | |
| SCHEMBL10423802 | 0.65 | — | — | |
| SCHEMBL2680263 | 0.63 | — | — | |
| SCHEMBL18791140 | 0.62 | — | — | |
| SCHEMBL19370410 | 0.62 | — | — | |
| SCHEMBL10882678 | 0.59 | MIF (0.34) | — | |
| SCHEMBL6030190 | 0.59 | NOTUM (0.58) | — | |
| SCHEMBL18678762 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484453-B | Derivatives of imidazo [1, 2-alpha ] pyridine-2-carboxamides, their preparation and their use in therapy | SANOFI AVENTIS | 2012-07-04 | — | — | CN | disclosed |
| EP-2041133-B1 | DERIVATIVES OF IMIDAZO [1,2-A]PYRIDINE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2010-10-13 | — | — | EP | disclosed |
| CN-101484453-A | Derivatives of imidazo [1, 2-alpha ] pyridine-2-carboxamides, their preparation and their use in therapy | SANOFI AVENTIS (FR) | 2009-07-15 | — | — | CN | disclosed |
| EP-2041133-A1 | DERIVATIVES OF IMIDAZO [1,2-A]PYRIDINE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008003856-A1 | DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2008-01-10 | — | — | WO | disclosed |