SCHEMBL10423802

SCHEMBL10423802

Nc1cn(Cn2cc(N)nn2)nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2680263 0.82
SCHEMBL18752143 0.82
SCHEMBL18678762 0.77
SCHEMBL14839430 0.75
SCHEMBL22576334 0.75 ACHE (0.38)
SCHEMBL19010785 0.73 GBA1 (0.41)
SCHEMBL7600967 0.71 SMPD1 (0.56)
SCHEMBL10065962 0.68 DPP4 (0.39)
SCHEMBL15747304 0.67 DGAT1 (0.32)
SCHEMBL197556 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4904564-A PHENOLIC-FORMALDEHYDE NOVOLAK; DIAZO SENSITIZER; IMIDAZOLE, BENZIMIDAZOLE, TRIAZOLE OR INDAZOLE TO INCREASE SOLUBILITY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1990-02-27 US disclosed
EP-0139090-B1 PROCESS FOR THE PRE-TREATMENT OF POLYIMIDES SCHERING AKTIENGESELLSCHAFT (DE) 1988-07-27 EP disclosed
US-4517254-A ALKALI METAL HYDROXIDE, AMINOALKYLPOLYACID COMPOUNT SCHERING AKTIENGESELLSCHAFT (DE) 1985-05-14 US disclosed
EP-0139090-A1 Process for the pre-treatment of polyimides SCHERING AKTIENGESELLSCHAFT (DE) 1985-05-02 EP disclosed