Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 3/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367937 | 1.00 | MEN1 (0.52) | MEN1KMT2AGAATP53HCRTR1 | |
| SCHEMBL5641690 | 0.96 | TP53 (0.51) | MEN1KMT2AGAATP53HCRTR1 | |
| SCHEMBL5641692 | 0.96 | TP53 (0.51) | MEN1KMT2AGAATP53HCRTR1 | |
| SCHEMBL3367943 | 0.92 | MEN1 (0.52) | MEN1KMT2AGAATP53HCRTR1 | |
| SCHEMBL5641698 | 0.89 | TP53 (0.50) | MEN1KMT2AGAATP53HCRTR1 | |
| SCHEMBL3366709 | 0.83 | OXTR (0.53) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL3366627 | 0.83 | OXTR (0.59) | KMT2AALDH1A1OXTRAVPR1APOLB | |
| SCHEMBL3364066 | 0.77 | TP53 (0.64) | MEN1KMT2AGAATP53HCRTR1 | |
| SCHEMBL3364069 | 0.77 | TP53 (0.64) | MEN1KMT2AGAATP53HCRTR1 | |
| SCHEMBL3366690 | 0.69 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | claimed |