Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366289 | 1.00 | HPRT1 (0.52) | HPRT1CYP1A2CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL30854669 | 0.80 | CYP1A2 (0.52) | HPRT1CYP1A2CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL6935198 | 0.79 | HPRT1 (0.71) | HPRT1CYP1A2CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL806448 | 0.78 | CYP1A2 (0.61) | HPRT1CYP1A2CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL7834992 | 0.78 | HPRT1 (0.47) | HPRT1CYP1A2CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL3110794 | 0.78 | HPRT1 (0.47) | HPRT1CYP1A2CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL15352353 | 0.78 | HPRT1 (0.47) | HPRT1CYP1A2CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL15352078 | 0.78 | HPRT1 (0.47) | HPRT1CYP1A2CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL21554160 | 0.78 | HPRT1 (0.47) | HPRT1CYP1A2CYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL15352082 | 0.78 | NQO2 (0.61) | HPRT1CYP1A2ALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946476-B1 | 5,7-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE THEREOF IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-21 | — | — | EP | claimed |
| EP-0946474-B1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-07 | — | — | EP | claimed |
| US-6159561-A | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | claimed |
| EP-0916713-A1 | Chiral smectic liquid crystal mixture containing 1,3-difluoronaphthalenes | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-05-19 | — | — | EP | claimed |
| US-20240004296-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION | NISSAN CHEMICAL CORPORATION (JP) | 2024-01-04 | — | — | US | disclosed |
| CN-116419937-A | Composition for forming resist underlayer film | 日产化学株式会社 | 2023-07-11 | — | — | CN | disclosed |
| CN-115991815-A | Halogenated modified prepared photoresist resin material and preparation method thereof | 中国科学院长春应用化学研究所 | 2023-04-21 | — | — | CN | disclosed |
| WO-2022107759-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION | 日産化学株式会社 | 2022-05-27 | — | — | WO | disclosed |
| US-10793584-B2 | Naphthobischalcogenadiazole derivative and production method therefor | OSAKA UNIVERSITY (JP) | 2020-10-06 | — | — | US | disclosed |
| US-20190337966-A1 | NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR | OSAKA UNIVERSITY (JP) | 2019-11-07 | — | — | US | disclosed |
| EP-3564245-A1 | NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR | Osaka University (JP) | 2019-11-06 | — | — | EP | disclosed |
| WO-2018123207-A1 | NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR | 国立大学法人大阪大学 | 2018-07-05 | — | — | WO | disclosed |
| EP-0916713-A1 | Chiral smectic liquid crystal mixture containing 1,3-difluoronaphthalenes | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998027037-A1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |
| US-5756730-A | Process for preparing analgesic compounds | SANKYO COMPANY, LIMITED (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5656758-A | AMIDATION OF AN AMINE-CONTAINING THIOMORPHOLINE OR PIPERAZINE COMPOUND | SANKYO COMPANY, LIMITED (JP) | 1997-08-12 | — | — | US | disclosed |
| US-5512567-A | KAPPA-RECEPTOR AGONISTS | SANKYO COMPANY, LIMITED (JP) | 1996-04-30 | — | — | US | disclosed |
| US-5270327-A | Piperidine derivatives | SANKYO COMPANY, LIMITED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0356247-B1 | ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES | Sankyo Company Limited (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0356247-A1 | Analgesic carboxylic acid amide derivatives | Sankyo Company Limited (JP) | 1990-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793584-B2 | Naphthobischalcogenadiazole derivative and production method therefor | CYP24A1, CYP26B1, CYP21A2 | HPRT1 707/4885CYP1A2 115/4885CYP2A6 96/4885 |
| US-20190337966-A1 | NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR | CYP24A1, CYP26B1, CYP21A2 | HPRT1 707/4885CYP1A2 115/4885CYP2A6 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.