SCHEMBL3368447

SCHEMBL3368447

O=C(O)c1ccnc(-c2ncccc2O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 12/20 0.61
KDM5C P41229 7/20 0.61
KDM3A Q9Y4C1 6/20 0.61
KDM4A O75164 6/20 0.61
KDM2A Q9Y2K7 5/20 0.61
KDM4E B2RXH2 4/20 0.61
KDM6B O15054 4/20 0.61
P4HA1 P13674 1/20 0.51
KDM2B Q8NHM5 2/20 0.50
KDM5B Q9UGL1 6/20 0.49
KDM4B O94953 3/20 0.49
JMJD6 Q6NYC1 1/20 0.48
KMO O15229 1/20 0.48
KDM5A P29375 3/20 0.47
KDM4D Q6B0I6 2/20 0.47
TET3 O43151 1/20 0.47
BBOX1 O75936 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
ASPH Q12797 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15238292 0.83 KDM4C (0.59) KDM4CKDM5CKDM3AKDM4AKDM2A
SCHEMBL28999921 0.80 KDM4C (0.69) KDM4CKDM5CKDM3AKDM4AKDM2A
SCHEMBL70700 0.78 KDM4C (0.78) KDM4CKDM5CKDM3AKDM4AKDM2A
SCHEMBL29407015 0.78 KDM4C (0.78) KDM4CKDM5CKDM3AKDM4AKDM2A
SCHEMBL23303939 0.77 KMO (0.67) KDM4CKDM5CKDM3AKDM4AKDM2A
SCHEMBL30318846 0.77 KMO (0.67) KDM4CKDM5CKDM3AKDM4AKDM2A
SCHEMBL25221788 0.77 KDM4C (0.75) KDM4CKDM5CKDM3AKDM4AKDM2A
SCHEMBL25220048 0.77 KDM4C (0.75) KDM4CKDM5CKDM3AKDM4AKDM2A
Hydrochloric Acid SCHEMBL6018233 0.77 KDM4C (0.75) KDM4CKDM5CKDM3AKDM4AKDM2A
SCHEMBL5670010 0.77 KDM4C (0.75) KDM4CKDM5CKDM3AKDM4AKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010018458-A2 PHENOL DERIVATIVES AND METHODS OF USE THEREOF CRYSTALGENOMICS, INC. (KR) 2010-02-18 WO claimed
WO-2010018458-A2 PHENOL DERIVATIVES AND METHODS OF USE THEREOF CRYSTALGENOMICS, INC. (KR) 2010-02-18 WO disclosed