Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14012505 | 0.89 | MAOA (0.58) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3370484 | 0.89 | MAOA (0.58) | MAOACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL3368277 | 0.89 | MAOA (0.57) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3429061 | 0.87 | MAOA (0.59) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3372319 | 0.85 | MAOA (0.56) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13335077 | 0.83 | MAOA (0.58) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3367260 | 0.83 | MAOA (0.58) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14012842 | 0.83 | MAOA (0.49) | MAOACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL3372849 | 0.83 | MAOA (0.57) | MAOACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL3429802 | 0.83 | MAOA (0.49) | MAOACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646629-B1 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK SHARP & DOHME (US) | 2010-06-23 | — | — | EP | claimed |