SCHEMBL3368787

SCHEMBL3368787

Ic1ccc(-c2nc(-c3nc(-c4ccc(I)cc4)c(-c4ccc(I)cc4)[nH]3)[nH]c2-c2ccc(I)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 11/20 0.63
MAPK12 P53778 11/20 0.63
MAPK11 Q15759 11/20 0.63
MAPK14 Q16539 11/20 0.63
GCGR P47871 7/20 0.63
RAF1 P04049 4/20 0.51
MAPK9 P45984 2/20 0.51
PRKD3 O94806 1/20 0.51
MAP4K4 O95819 1/20 0.51
FRK P42685 1/20 0.51
CSNK1A1 P48729 1/20 0.51
CSNK1D P48730 1/20 0.51
GSK3B P49841 1/20 0.51
PTK6 Q13882 1/20 0.51
PRKD2 Q9BZL6 1/20 0.51
CLK4 Q9HAZ1 1/20 0.51
NOX1 Q9Y5S8 2/20 0.49
PTPN1 P18031 1/20 0.47
MGAM O43451 1/20 0.47
MAPT P10636 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10143966 0.85 MAPK13 (0.73) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL3956357 0.81 MAPK13 (0.74) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL3371979 0.81 MAPK14 (0.74) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL3456136 0.81 MAPK13 (0.74) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL739928 0.80 MAPK13 (0.72) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL2650702 0.79 MAPK11 (1.00) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL5074753 0.77 MAPK13 (0.83) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL3455232 0.76 NOX1 (0.77) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL9748575 0.75 MAPK13 (0.83) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL16667652 0.75 MAPK13 (0.83) MAPK13MAPK12MAPK11MAPK14GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010063763-A1 GUMMING COMPOSITIONS WITH NANO-PARTICLES FOR IMPROVING SCRATCH SENSITIVITY IN IMAGE AND NON-IMAGE AREAS OF LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 2010-06-10 WO disclosed