Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.76 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.73 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.73 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.73 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.73 |
| ▸ | GCGR | P47871 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | RAF1 | P04049 | 4/20 | 0.73 |
| ▸ | TP53 | P04637 | 3/20 | 0.73 |
| ▸ | BRAF | P15056 | 2/20 | 0.73 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.71 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.71 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.71 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.71 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.71 |
| ▸ | FRK | P42685 | 2/20 | 0.71 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.71 |
| ▸ | GSK3B | P49841 | 2/20 | 0.71 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.71 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307418 | 0.93 | MAPK13 (0.85) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL18292488 | 0.93 | MAPK13 (0.85) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL9619859 | 0.93 | MAPK13 (0.85) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL252964 | 0.93 | MAPK13 (0.85) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL15401173 | 0.93 | MAPK13 (0.85) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL29587593 | 0.91 | CYP19A1 (0.72) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL31255400 | 0.91 | MAPK13 (0.83) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL14023448 | 0.91 | MAPK14 (0.88) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL12561713 | 0.91 | MAPK13 (0.83) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6467393 | 0.87 | NOX1 (1.00) | NOX1MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |