Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.64 |
| ▸ | ITGAV | P06756 | 16/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8739838 | 0.82 | ITGB3 (0.79) | ITGB3ITGAVITGA2B | |
| SCHEMBL6951971 | 0.78 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7916989 | 0.78 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL8739433 | 0.78 | ITGB3 (0.79) | ITGB3ITGAVITGA2B | |
| SCHEMBL13936150 | 0.73 | ITGB3 (0.85) | ITGB3ITGAVITGA2B | |
| SCHEMBL15086003 | 0.73 | ITGB3 (0.79) | ITGB3ITGAVITGA2B | |
| SCHEMBL8356952 | 0.73 | ITGB3 (0.60) | ITGB3ITGAVITGA2BPDK1PDK2 | |
| SCHEMBL7361487 | 0.72 | ITGB3 (0.64) | ITGB3ITGAVITGA2BPDK1PDK2 | |
| SCHEMBL245523 | 0.72 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL31321063 | 0.72 | ITGB3 (1.00) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428226-A1 | Antibody targeting compounds | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2003034995-A2 | INTEGRIN TARGETING COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2003-05-01 | — | — | WO | disclosed |