Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | GFER | P55789 | 2/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947174 | 0.92 | NPC1 (0.75) | ESR1ESR2NPC1RAB9AGFER | |
| SCHEMBL31532268 | 0.91 | ESR1 (0.69) | ESR1ESR2NPC1RAB9AGFER | |
| SCHEMBL26599357 | 0.91 | ESR1 (0.69) | ESR1ESR2NPC1RAB9AGFER | |
| SCHEMBL3288472 | 0.91 | NPC1 (0.78) | ESR1ESR2NPC1RAB9AGFER | |
| SCHEMBL15745637 | 0.91 | NPC1 (0.73) | ESR1ESR2NPC1RAB9AGFER | |
| SCHEMBL10045308 | 0.87 | NPC1 (0.68) | ESR1ESR2NPC1RAB9AGFER | |
| SCHEMBL2246180 | 0.87 | NPC1 (0.71) | ESR1ESR2NPC1RAB9AGFER | |
| SCHEMBL26660197 | 0.86 | ESR1 (0.62) | ESR1ESR2NPC1RAB9AGFER | |
| SCHEMBL3366096 | 0.86 | ESR1 (0.62) | ESR1ESR2NPC1RAB9AGFER | |
| SCHEMBL2244484 | 0.85 | NPC1 (0.66) | ESR1ESR2NPC1RAB9AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521798-B1 | SUNSCREENS | DSM IP ASSETS BV (NL) | 2010-01-27 | — | — | EP | disclosed |
| US-20060160976-A1 | Sunscreens | DSM IP ASSETS B.V. (NL) | 2006-07-20 | — | — | US | disclosed |
| EP-1521798-A1 | SUNSCREENS | DSM IP Assets B.V. (NL) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007592-A1 | SUNSCREENS | DSM IP ASSETS B.V. (NL) | 2004-01-22 | — | — | WO | disclosed |