Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.75 |
| ▸ | RAB9A | P51151 | 8/20 | 0.75 |
| ▸ | GFER | P55789 | 2/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745637 | 0.98 | NPC1 (0.73) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL3288472 | 0.98 | NPC1 (0.78) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL2246180 | 0.94 | NPC1 (0.71) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL10045308 | 0.94 | NPC1 (0.68) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL3368896 | 0.92 | ESR1 (0.69) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL22103728 | 0.92 | NPC1 (0.66) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL3288218 | 0.92 | NPC1 (0.66) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL2242200 | 0.92 | RAB9A (0.84) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL2244484 | 0.92 | NPC1 (0.66) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL2242175 | 0.92 | NPC1 (0.65) | NPC1RAB9AGFERHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9146483-B2 | Photoreceptor, method for preparing photoreceptor, and image forming apparatus and process cartridge using the photoreceptor | RICOH COMPANY, LTD. (JP) | 2015-09-29 | — | — | US | disclosed |
| US-20140234763-A1 | IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140234763-A1 | IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20130243483-A1 | PHOTORECEPTOR, METHOD FOR PREPARING PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR | RICOH COMPANY, LTD. (JP) | 2013-09-19 | — | — | US | disclosed |
| US-20130122410-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR IMAGE FORMING APPARATUS USING THE ELCTROPHOTOGRAPHIC PHOTOCONDUCTOR | RICOH COMPANY, LTD. (JP) | 2013-05-16 | — | — | US | disclosed |
| US-20130122410-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR IMAGE FORMING APPARATUS USING THE ELCTROPHOTOGRAPHIC PHOTOCONDUCTOR | RICOH COMPANY, LTD. (JP) | 2013-05-16 | — | — | US | disclosed |