SCHEMBL3369241

SCHEMBL3369241

O=C(COc1ccccc1)N1CCCC1c1nnc(-c2ccc(-c3ccccc3)cc2)o1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CPT1A P50416 20/20 0.57
CPT2 P23786 13/20 0.57
CPT1B Q92523 4/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3366773 0.93 CPT1A (0.66) CPT1ACPT2CPT1B
SCHEMBL3365286 0.91 CPT1A (0.61) CPT1ACPT2CPT1B
SCHEMBL3369456 0.89 HCRTR1 (0.54) CPT1ACPT2CPT1B
SCHEMBL6068996 0.84 HCRTR1 (0.54) CPT1ACPT2CPT1B
SCHEMBL3367292 0.84 HCRTR1 (0.50) CPT1ACPT2CPT1B
SCHEMBL3366778 0.84 HCRTR1 (0.58)
SCHEMBL3366771 0.82 CPT1A (0.53) CPT1ACPT2CPT1B
SCHEMBL3366080 0.82 HCRTR1 (0.55)
SCHEMBL3370370 0.81 HCRTR1 (0.60)
SCHEMBL3366901 0.81 HCRTR1 (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1532141-B1 2-PYRROLIDIN-2-YL- [1,3,4]-OXADIAZOLE DERIVATIVES AND THE USE OF THE SAME AS ANTIDEPRESSANTS GRUENENTHAL GMBH (DE) 2010-10-13 EP disclosed