Glycyl Proline

Glycyl Proline

SCHEMBL336928

Cc1cc(=O)oc2cc(N)ccc12.NCC(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.53
ALDH1A1 P00352 7/20 0.53
HPGD P15428 5/20 0.53
HSD17B10 Q99714 3/20 0.53
GAA P10253 3/20 0.53
GLA P06280 2/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
CA9 Q16790 1/20 0.53
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
RECQL P46063 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycyl Proline SCHEMBL4624321 0.99 KDM4E (0.52) KDM4EALDH1A1HPGDHSD17B10GAA
Glycyl Proline SCHEMBL4196661 0.99 KDM4E (0.52) KDM4EALDH1A1HPGDHSD17B10GAA
Glycyl Proline SCHEMBL16859388 0.89 KDM4E (0.44) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL4189547 0.82 PREP (0.49) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL740253 0.82 KDM4E (0.61) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL11440079 0.82 KDM4E (0.61) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL30182028 0.82 KDM4E (0.61) KDM4EALDH1A1HPGDHSD17B10GAA
Bromide SCHEMBL29543703 0.81 KDM4E (0.60) KDM4EALDH1A1HPGDHSD17B10GAA
Bromide SCHEMBL30261894 0.81 KDM4E (0.60) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL16162942 0.80 KDM4E (0.45) KDM4EALDH1A1HPGDHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015024576-A1 POLYMER-BOUND IODINE AS A QUENCHER FOR FLUORESCENCE MEASUREMENTS TESTO AG (DE) 2015-02-26 WO claimed
CN-101551333-B Composition for cell permeabilization comprising nog, hmp, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP 2012-11-28 CN claimed
US-8097404-B2 Composition and method for cell permeabilization comprising N-octyl-β-D-glucopyranoside, sodium polyphosphates, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORPORATION (US) 2012-01-17 US claimed
EP-2107119-B1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2010-05-12 EP claimed
EP-2107119-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane Millipore Corporation (US) 2009-10-07 EP claimed
CN-101551333-A Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2009-10-07 CN claimed
US-20090246822-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane EMD MILLIPORE CORPORATION 2009-10-01 US claimed
EP-1352083-B1 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS INC (US) 2005-10-26 EP claimed
WO-1995000660-A1 METHOD FOR ASSESSING MICROORGANISM VIABILITY CHEMUNEX (FR) 1995-01-05 WO claimed
CN-101551333-B Composition for cell permeabilization comprising nog, hmp, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP 2012-11-28 CN disclosed
US-8097404-B2 Composition and method for cell permeabilization comprising N-octyl-β-D-glucopyranoside, sodium polyphosphates, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORPORATION (US) 2012-01-17 US disclosed
EP-2107119-B1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2010-05-12 EP disclosed
EP-2107119-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane Millipore Corporation (US) 2009-10-07 EP disclosed
CN-101551333-A Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2009-10-07 CN disclosed
US-20090246822-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane EMD MILLIPORE CORPORATION 2009-10-01 US disclosed
WO-1995000660-A1 METHOD FOR ASSESSING MICROORGANISM VIABILITY CHEMUNEX (FR) 1995-01-05 WO disclosed
EP-0333560-B1 Process for quantitative determination of micro organismes CHEMUNEX (FR) 1994-04-27 EP disclosed
WO-1989008714-A1 QUALITITIVE OR QUANTITITIVE PROCESS FOR RESEARCHING MICROORGANISMS, INSTALLATION FOR APPLICATION OF SAID PROCESS CHEMUNEX (FR) 1989-09-21 WO disclosed
EP-0333560-A1 Process for quantitative determination of micro organismes CHEMUNEX (FR) 1989-09-20 EP disclosed