SCHEMBL4189547

SCHEMBL4189547

Cc1cc(=O)oc2cc(N)ccc12.O=C(NCC(=O)N1CCC[C@H]1C(=O)O)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PREP P48147 2/20 0.49
ACE P12821 1/20 0.45
MAOB P27338 3/20 0.43
FKBP1A P62942 4/20 0.42
MAOA P21397 2/20 0.42
NPC1 O15118 1/20 0.42
CASP3 P42574 1/20 0.42
RAB9A P51151 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29354123 0.86 ALDH1A1 (0.51) PREPMAOANPC1RAB9AKDM4E
SCHEMBL740254 0.86 ALDH1A1 (0.51) PREPMAOANPC1RAB9AKDM4E
SCHEMBL30377081 0.86 ALDH1A1 (0.51) PREPMAOANPC1RAB9AKDM4E
SCHEMBL8202867 0.85 PREP (0.47) PREPMAOBFKBP1AMAOANPC1
Glycyl Proline SCHEMBL336928 0.82 KDM4E (0.53) MAOBRAB9AKDM4EALDH1A1HPGD
Glycyl Proline SCHEMBL4624321 0.81 KDM4E (0.52) MAOBRAB9AKDM4EALDH1A1HPGD
Glycyl Proline SCHEMBL4196661 0.81 KDM4E (0.52) MAOBRAB9AKDM4EALDH1A1HPGD
SCHEMBL11764594 0.80 PREP (0.71) PREPACEFKBP1AALDH1A1KMT2A
SCHEMBL2228388 0.80 PREP (0.71) PREPACEFKBP1AALDH1A1KMT2A
SCHEMBL11761001 0.78 PREP (0.67) PREPACEFKBP1AALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1352083-B1 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS INC (US) 2005-10-26 EP claimed
EP-1352083-A2 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BioControl Systems, Inc. (US) 2003-10-15 EP claimed
US-20020058298-A1 Compositions and methods for detecting target microorganisms in a sample BIOCONTROL SYSTEM, INC. (US) 2002-05-16 US claimed
WO-2002018625-A2 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS, INC. (US) 2002-03-07 WO claimed
US-6022698-A Method and components for the detection of yeasts and/or molds in a sample IDEXX LABORATORIES, INCORPORATED (US) 2000-02-08 US claimed
EP-0946746-A1 METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE IDEXX LABORATORIES, INC. (US) 1999-10-06 EP claimed
US-5854011-A Method and components for the detection of yeasts and/or molds in a sample IDEXX LABORATORIES INCORPORATED (US) 1998-12-29 US claimed
WO-1998027223-A1 METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE IDEXX LABORATORIES, INCORPORATED (US) 1998-06-25 WO claimed
US-7560246-B2 Compositions and methods for detecting target microorganisms in a sample BIOCONTROL SYSTEMS, INC. (US) 2009-07-14 US disclosed
EP-0870054-B1 METHOD AND COMPOSITION FOR DETECTING BACTERIAL CONTAMINATION IN FOOD PRODUCTS BIOCONTROL SYSTEMS INC (US) 2008-07-30 EP disclosed
EP-1352083-B1 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS INC (US) 2005-10-26 EP disclosed
EP-1352083-A2 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BioControl Systems, Inc. (US) 2003-10-15 EP disclosed
US-20020058298-A1 Compositions and methods for detecting target microorganisms in a sample BIOCONTROL SYSTEM, INC. (US) 2002-05-16 US disclosed
WO-2002018625-A2 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS, INC. (US) 2002-03-07 WO disclosed
EP-0946746-A1 METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE IDEXX LABORATORIES, INC. (US) 1999-10-06 EP disclosed
US-5854011-A Method and components for the detection of yeasts and/or molds in a sample IDEXX LABORATORIES INCORPORATED (US) 1998-12-29 US disclosed
WO-1998027223-A1 METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE IDEXX LABORATORIES, INCORPORATED (US) 1998-06-25 WO disclosed