SCHEMBL336932

SCHEMBL336932

CC(C)(C)OOC1(c2ccccc2)OC(=O)c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.61
ATM Q13315 1/20 0.61
NPSR1 Q6W5P4 8/20 0.60
GAA P10253 2/20 0.60
CYP2C9 P11712 5/20 0.57
CYP2C19 P33261 5/20 0.57
CYP3A4 P08684 4/20 0.57
L3MBTL1 Q9Y468 4/20 0.57
CYP1A2 P05177 2/20 0.57
HTT P42858 1/20 0.57
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
TDP1 Q9NUW8 3/20 0.53
RECQL P46063 2/20 0.53
CFTR P13569 1/20 0.49
GOPC Q9HD26 1/20 0.49
MAPT P10636 3/20 0.48
LMNA P02545 3/20 0.41
PKM P14618 1/20 0.38
HSP90AA1 P07900 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11138146 0.89 SMN1; SMN2 (0.49) SMN1; SMN2ATMNPSR1GAACYP2C9
SCHEMBL10745566 0.80 SMN1; SMN2 (0.69) SMN1; SMN2ATMNPSR1GAACYP2C9
SCHEMBL3887315 0.76 SMN1; SMN2 (1.00) SMN1; SMN2ATMNPSR1GAACYP2C9
SCHEMBL9767700 0.75 NPSR1 (0.57) SMN1; SMN2ATMNPSR1GAACYP2C9
SCHEMBL1550971 0.75 NPSR1 (0.76) SMN1; SMN2ATMNPSR1GAACYP2C9
SCHEMBL11753756 0.75 SMN1; SMN2 (0.62) SMN1; SMN2ATMNPSR1GAACYP2C9
SCHEMBL11836216 0.73 SMN1; SMN2 (0.43) SMN1; SMN2ATMNPSR1GAACYP2C9
SCHEMBL9767707 0.69 NPSR1 (0.53) SMN1; SMN2ATMNPSR1GAACYP2C9
SCHEMBL11752714 0.69 SMN1; SMN2 (0.55) SMN1; SMN2ATMNPSR1GAACYP2C9
SCHEMBL9767713 0.68 NPSR1 (0.49) SMN1; SMN2ATMNPSR1GAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841375-B2 Isolable and redispersable transition metal nanoparticles their preparation and use as IR absorbers BASF SE (DE) 2014-09-23 US claimed
US-8618224-B2 Viscosity breaking process for olefin polymers BASF SE (DE) 2013-12-31 US claimed
US-20130245203-A1 Viscosity Breaking Process for Olefin Polymers BASF SE (DE) 2013-09-19 US claimed
EP-2195132-B1 METHOD FOR PREPARATION OF ISOLABLE AND REDISPERSABLE TRANSITION METAL NANOPARTICLES BASF SE (DE) 2012-06-06 EP claimed
JP-2010540769-A 2010-12-24 JP claimed
US-20100261827-A1 ISOLABLE AND REDISPERSABLE TRANSITION METAL NANOPARTICLES THEIR PREPARATION AND USE AS IR ABSORBERS BASF SE (DE) 2010-10-14 US claimed
EP-2195132-A1 ISOLABLE AND REDISPERSABLE TRANSITION METAL NANOPARTICLES THEIR PREPARATION AND USE AS IR ABSORBERS BASF SE (DE) 2010-06-16 EP claimed
JP-2009527608-A 2009-07-30 JP claimed
EP-1115765-B1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS CIBA HOLDING INC (CH) 2009-06-24 EP claimed
WO-2009056401-A1 ISOLABLE AND REDISPERSABLE TRANSITION METAL NANOPARTICLES THEIR PREPARATION AND USE AS IR ABSORBERS BASF SE (CH) 2009-05-07 WO claimed
US-6620892-B1 Increasing fluidity index by cuts of chains using stable nitroxyl free radical compound ATOFINA (FR) 2003-09-16 US claimed
EP-1192192-B1 METHOD FOR THE PRODUCTION OF A CONTROLLED RHEOLOGICAL POLYPROPYLENE RESIN ATOFINA (FR) 2003-03-26 EP claimed
US-6525151-B1 Attaching stable nitroxyl radical to increase activity toward chemical modification and copolymerizing; adhesives; polymer blend compatibilizers or toughening agents CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-25 US claimed
US-6521710-B1 Grafting of ethylenically unsaturated monomers onto polymers CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-18 US claimed
EP-1115765-A1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS Ciba SC Holding AG (CH) 2001-07-18 EP claimed
WO-2000014134-A1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-16 WO claimed
EP-0009268-B1 PROCESS FOR CROSS-LINKING SHAPED NON-POLAR SYNTHETIC RESINS AND ELECTRIC OBJECTS INSULATED WITH SAID CROSSLINKED RESINS AKZO N.V. (NL) 1982-12-01 EP claimed
US-4322273-A TREATING A MIXTURE OF ACYCLIC OLEFIN-BASED POLYMER AND POLAR PERESTER, PERKETAL, OR ESTER- CONTAINING PEROXY COMPOUND; WITH HIGH-FREQUENY ALTERNATING CURRENT DIELECTRICS AKZONA INCORPORATED (US) 1982-03-30 US claimed
EP-0009268-A1 Process for cross-linking shaped non-polar synthetic resins and electric objects insulated with said crosslinked resins AKZO N.V. (NL) 1980-04-02 EP claimed
US-3956253-A PEROXIDE CROSSLINKING AGENT, COMPRESSION, PLASTICIZING RUHRCHEMIE AKTIENGESELLSCHAFT (DT) 1976-05-11 US claimed