Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767700 | 0.72 | NPSR1 (0.57) | NPSR1CYP2C9CYP2C19CYP3A4RECQL | |
| SCHEMBL9767713 | 0.72 | NPSR1 (0.49) | NPSR1CYP2C9CYP2C19CYP3A4RECQL | |
| SCHEMBL10745566 | 0.69 | SMN1; SMN2 (0.69) | NPSR1CYP2C9CYP2C19CYP3A4RECQL | |
| SCHEMBL336932 | 0.69 | SMN1; SMN2 (0.61) | NPSR1CYP2C9CYP2C19CYP3A4RECQL | |
| SCHEMBL3887315 | 0.66 | SMN1; SMN2 (1.00) | NPSR1CYP2C9CYP2C19CYP3A4RECQL | |
| SCHEMBL29867855 | 0.66 | GAA (0.43) | GAAMEN1KMT2ATDP1LMNA | |
| SCHEMBL1550971 | 0.65 | NPSR1 (0.76) | NPSR1CYP2C9CYP2C19CYP3A4RECQL | |
| SCHEMBL11753756 | 0.65 | SMN1; SMN2 (0.62) | NPSR1CYP2C9CYP2C19CYP3A4RECQL | |
| SCHEMBL11932064 | 0.61 | CFTR (0.61) | NPSR1CYP2C9CYP2C19CYP3A4RECQL | |
| SCHEMBL11138146 | 0.60 | SMN1; SMN2 (0.49) | NPSR1CYP2C9CYP2C19CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2117012-A | — | — | None | — | — | JP | disclosed |
| JP-3006246-A | — | — | None | — | — | JP | disclosed |
| JP-H036246-A | CROSSLINKING AGENT FOR POLYMER | NIPPON OIL & FATS CO LTD | 1991-01-11 | — | — | JP | disclosed |
| JP-H02117012-A | BRIDGING POLYOLEFIN INSULATING POWER CABLE | FURUKAWA ELECTRIC CO LTD:THE | 1990-05-01 | — | — | JP | disclosed |