Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7052895 | 0.89 | — | — | |
| Methane SCHEMBL11592345 | 0.52 | — | — | |
| SCHEMBL6377177 | 0.52 | — | — | |
| Methane SCHEMBL9435911 | 0.52 | — | — | |
| Ethane SCHEMBL16975097 | 0.52 | — | — | |
| Methane SCHEMBL23040988 | 0.52 | — | — | |
| Ethane SCHEMBL1523046 | 0.52 | — | — | |
| Methane SCHEMBL5586176 | 0.52 | — | — | |
| Ethane SCHEMBL7169030 | 0.52 | — | — | |
| Methane SCHEMBL1162076 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853549-B1 | FILMS COMPRISING METALLOCENE CATALYZED POLYETHYLENE | CHEVRON PHILLIPS CHEMICAL CO (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2002072641-A1 | METHOD FOR MAKING AND USING A METALLOCENE CATALYST SYSTEM | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2002-09-19 | — | — | WO | disclosed |
| US-6355359-B1 | CLARITY | PHILLIPS PETROLEUM COMPANY | 2002-03-12 | — | — | US | disclosed |
| CN-1070772-C | Films made from metallocene-catalytically produced polyethylene | PHILLIPS PETROLEUM CO (US) | 2001-09-12 | — | — | CN | disclosed |
| US-6214469-B1 | Films comprising metallocene catalyzed polyethylene | PHILLIPS PETROLEUM COMPANY | 2001-04-10 | — | — | US | disclosed |
| EP-0853549-A4 | FILMS COMPRISING METALLOCENE CATALYZED POLYETHYLENE | PHILLIPS PETROLEUM CO (US) | 1999-08-18 | — | — | EP | disclosed |
| US-5830958-A | Polynuclear metallocene preparation and use | PHILLIPS PETROLEUM COMPANY (US) | 1998-11-03 | — | — | US | disclosed |
| CN-1193298-A | Films made from metallocene-catalytically produced polyethylene | PHILLIPS PETROLEUM CO (US) | 1998-09-16 | — | — | CN | disclosed |
| EP-0853549-A1 | FILMS COMPRISING METALLOCENE CATALYZED POLYETHYLENE | Phillips Petroleum Company (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997006951-A1 | FILMS COMPRISING METALLOCENE CATALYZED POLYETHYLENE | PHILLIPS PETROLEUM COMPANY (US) | 1997-02-27 | — | — | WO | disclosed |