Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867748 | 0.84 | CHRM2 (0.31) | MEN1HTTKMT2A | |
| SCHEMBL11451574 | 0.79 | MEN1 (0.45) | MEN1HTTKMT2A | |
| SCHEMBL31457109 | 0.78 | FOLH1 (0.33) | — | |
| SCHEMBL28093354 | 0.76 | — | — | |
| SCHEMBL12497665 | 0.76 | MEN1 (0.54) | MEN1HTTKMT2A | |
| SCHEMBL15971664 | 0.75 | IDUA (0.32) | — | |
| SCHEMBL4716948 | 0.74 | CHRM2 (0.32) | — | |
| SCHEMBL21751551 | 0.73 | KDM4E (0.40) | MEN1KMT2A | |
| SCHEMBL31727940 | 0.71 | CHRM2 (0.34) | — | |
| SCHEMBL21751634 | 0.71 | CHRM2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349469-A1 | Pharmaceutical product having skin regenerating properties based on the active principle of mimosa tenuiflora, and process for producing same | Tellez Perez, Julio (MX) | 1990-01-03 | — | — | EP | claimed |
| EP-1619191-B1 | Process for producing optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl] acetic acid derivatives | KANEKA CORP (JP) | 2010-10-27 | — | — | EP | disclosed |
| EP-1394157-B1 | Process for the preparation of 3,5-dihydroxy substituted esters as intermediates for producing optically active 2-(6-(hydroxymethyl)-1,3-dioxan-4-yl) acetic acid dervatives | KANEKA CORP (JP) | 2007-10-17 | — | — | EP | disclosed |
| EP-1288213-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL|ACETIC ACID DERIVATIVES | KANEKA CORP (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-20060246557-A1 | Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives | KANEKA CORPORATION (JP) | 2006-11-02 | — | — | US | disclosed |
| US-7094594-B2 | Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives | KANEKA CORPORATION (JP) | 2006-08-22 | — | — | US | disclosed |
| EP-1619191-A2 | Process for producing optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl] acetic acid derivatives | KANEKA CORPORATION (JP) | 2006-01-25 | — | — | EP | disclosed |
| US-6903225-B2 | Process for producing optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]acetic acid derivatives | KANEKA CORPORATION (JP) | 2005-06-07 | — | — | US | disclosed |
| US-20050080277-A1 | Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives | KANEKA CORPORATION (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-1024139-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 2-(6-(HYDROXYMETHYL)-1,3-DIOXAN-4-YL) ACETIC ACID DERIVATIVES | KANEKA CORP (JP) | 2004-05-12 | — | — | EP | disclosed |
| EP-1288213-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-20030040634-A1 | Process for producing optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4yl]acetic acid derivatives | KANEKA CORPORATION (JP) | 2003-02-27 | — | — | US | disclosed |
| US-6472544-B1 | REACTING ACETIC ACID DERIVATIVE WITH AN ENOLATE, REDUCING WITH A MICROORGANISM, ACETALIZING IN PRESENCE OF ACID CATALYST THEN ALKALINE SAPONIFICATION; NO SPECIAL EQUIPMENT OR SUPER LOW TEMPERATURE REQUIRED; INEXPENSIVE STARTING MATERIALS | KANEKA CORPORATION (JP) | 2002-10-29 | — | — | US | disclosed |
| US-20010041796-A1 | Pentacyclic compound | TERASAWA HIROFUMI (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-0826688-B1 | PENTACYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6211363-B1 | TAXANE COMPOUNDS; ANTITUMOR AGENTS | DAIICHI PHARAMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-1024139-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 2- 6-(HYDROXYMETHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2000-08-02 | — | — | EP | disclosed |
| US-6075140-A | A TAXOL DERIVATIVE CONTAINING PENTACYCLIC RING IN WHICH 9 AND 10 POSITION HYDROXYL GROUP ARE CHANGED TO CYCLIC ACETAL GROUP IS USEFUL AS ANTITUMOR AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-06-13 | — | — | US | disclosed |
| EP-0826688-A1 | PENTACYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0349469-A1 | Pharmaceutical product having skin regenerating properties based on the active principle of mimosa tenuiflora, and process for producing same | Tellez Perez, Julio (MX) | 1990-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040634-A1 | Process for producing optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4yl]acetic acid derivatives | HAAO, APEH, AADAC | MEN1 2905/4885HTT 1256/4885KMT2A 627/4885 |
| US-20010041796-A1 | Pentacyclic compound | RPL31, BCOR, OXER1 | MEN1 3289/4885HTT 4326/4885KMT2A 2812/4885 |
| US-20060246557-A1 | Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives | HAAO, APEH, HPD | MEN1 1586/4885HTT 1172/4885KMT2A 1181/4885 |
| US-20050080277-A1 | Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives | HAAO, APEH, HPD | MEN1 2042/4885HTT 1354/4885KMT2A 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.