Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369053 | 0.87 | F10 (0.57) | F10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3373371 | 0.86 | F10 (0.56) | F10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1382657 | 0.86 | F10 (1.00) | F10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3371388 | 0.81 | F10 (0.51) | F10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3372771 | 0.81 | F10 (0.51) | F10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3368156 | 0.80 | F10 (0.50) | F10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3372955 | 0.80 | F10 (0.50) | F10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3368146 | 0.74 | F10 (0.46) | F10 | |
| SCHEMBL1381284 | 0.73 | F10 (0.76) | F10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1382719 | 0.72 | F10 (0.75) | F10MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-B1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-07-21 | — | — | EP | claimed |