Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381239 | 0.86 | F10 (0.67) | F10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3373371 | 0.85 | F10 (0.56) | F10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3371388 | 0.85 | F10 (0.51) | F10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3372955 | 0.82 | F10 (0.50) | F10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3368156 | 0.82 | F10 (0.50) | F10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3369686 | 0.81 | F10 (0.76) | F10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3369053 | 0.81 | F10 (0.57) | F10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3372965 | 0.74 | F10 (0.66) | F10 | |
| SCHEMBL3367502 | 0.73 | F10 (0.48) | F10 | |
| SCHEMBL1384352 | 0.71 | F10 (0.68) | F10ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-B1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-07-21 | — | — | EP | claimed |