SCHEMBL3369956

SCHEMBL3369956

CC(C)n1c(=O)n(C(=O)NCC2CCN(CCC(OC(N)=O)c3ccccc3)CC2)c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 5/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15103560 0.94 HTR4 (0.56) HTR4
SCHEMBL2333635 0.94 HTR4 (0.55) HTR4
SCHEMBL2337050 0.94 HTR4 (0.55) HTR4
SCHEMBL15103613 0.93 HTR4 (0.54) HTR4
SCHEMBL15103569 0.87 HTR4 (0.51) HTR4
SCHEMBL2337262 0.87 HTR4 (0.63) HTR4
SCHEMBL2333382 0.86 HTR4 (0.56) HTR4
SCHEMBL3300529 0.84 HTR4 (0.60) HTR4
SCHEMBL15103496 0.83 HTR4 (0.53) HTR4
SCHEMBL8261304 0.83 HTR4 (0.68) HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2358702-B1 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK BIOPHARMACEUTICALS CO LTD (KR) 2013-07-17 EP claimed
WO-2010044585-A2 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK HOLDINGS CO., LTD. (KR) 2010-04-22 WO claimed
EP-2358702-B1 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK BIOPHARMACEUTICALS CO LTD (KR) 2013-07-17 EP disclosed
WO-2010044585-A2 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK HOLDINGS CO., LTD. (KR) 2010-04-22 WO disclosed