Fluoride

Fluoride

SCHEMBL337023

CCN(S)CC.CCN(S)CC.CCN(S)CC.F.F.F

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 1/20 0.30
CYP2E1 P05181 1/20 0.30
PTGS1 P23219 1/20 0.30
HTT P42858 1/20 0.30
GSDMD P57764 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL384318 1.00
Fluoride SCHEMBL10788206 1.00
SCHEMBL384317 0.95
Ethane SCHEMBL2526199 0.91
Propane SCHEMBL2521863 0.91
SCHEMBL28950638 0.91
Ethane SCHEMBL4578616 0.87
Butane SCHEMBL2524930 0.87
Fluoride SCHEMBL28981522 0.86
Dimethyl Sulfoxide SCHEMBL5667863 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097164-B2 Process for preparing magnetic particles for selectively removing contaminants from solution ELECTRIC POWER RESEARCH INSTITUTE, INC. (US) 2012-01-17 US claimed
EP-2063433-B1 Process for preparing magnetic particles for selectively removing contaminants from solution ELECTRIC POWER RES INST (US) 2010-06-09 EP claimed
EP-2063433-A1 Process for preparing magnetic particles for selectively removing contaminants from solution Electric Power Research Institute, Inc. (US) 2009-05-27 EP claimed
US-20090120880-A1 Process for Preparing Magnetic Particles for Selectively Removing Contaminants from Solution ELECTRIC POWER RESEARCH INSTITUTE, INC. 2009-05-14 US claimed
CN-111278809-B Bicyclic sulfones and sulfoxides, and methods of use thereof 豪夫迈·罗氏有限公司 2024-06-25 CN disclosed
EP-4236963-A1 5ALPHA-HYDROXY-6BETA-[2-(1-H-IMIDAZOL-4-YL)-ETHYLAMINO]-CHOLESTAN-3BETA-OL ANALOGUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME FOR USE IN THE TREATMENT OF CANCER Dendrogenix (BE) 2023-09-06 EP disclosed
WO-2022090427-A1 5ALPHA-HYDROXY-6BETA-[2-(1-H-IMIDAZOL-4-YL)-ETHYLAMINO]-CHOLESTAN-3BETA-OL ANALOGUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME FOR USE IN THE TREATMENT OF CANCER DENDROGENIX (BE) 2022-05-05 WO disclosed
CN-111278809-A Bicyclic sulfones and sulfoxides, and methods of use thereof 豪夫迈·罗氏有限公司 2020-06-12 CN disclosed
US-10202372-B2 Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) 2019-02-12 US disclosed
EP-2885297-B1 TRISUBSTITUTED PYRIDO[3,2-D]PYRIMIDINES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTICAL USES CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) 2017-10-11 EP disclosed
US-20150203489-A1 TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF UNIVERSITE D'ORLEANS (FR) 2015-07-23 US disclosed
EP-2885297-A1 TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF Centre National de la Recherche Scientifique (C.N.R.S.) (FR) 2015-06-24 EP disclosed
US-5434175-A PARASITICIDES, INSECTICIDES AND MITICIDES ROUSSEL UCLAF (FR) 1995-07-18 US disclosed
US-5428043-A Tricyclic-cyclic amines as novel cholinesterase inhibitors PFIZER INC. (US) 1995-06-27 US disclosed
US-5395845-A Insecticides ROUSSEL-UCLAF (FR) 1995-03-07 US disclosed
EP-0632008-A1 Pentanoic acid derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1995-01-04 EP disclosed
US-5086047-A Controlling estrogen production; breast cancer ROUSSEL UCLAF, DEPARTMENT DES BREVETS (FR) 1992-02-04 US disclosed
EP-0441517-A2 Tricyclic amines as novel cholinesterase inhibitors PFIZER INC. (US) 1991-08-14 EP disclosed
US-4988684-A Steroids for the inhibition of aromatase for the treatment of cancer ROUSSEL UCLAF (FR) 1991-01-29 US disclosed
US-4808210-A WEED CONTROL ROUSSEL UCLAF (FR) 1989-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203489-A1 TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF DPYD, TYMP, RRM2B ABCB11 4014/4885CYP2E1 859/4885PTGS1 3804/4885
US-10202372-B2 Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof DPYD, TYMP, RRM2B ABCB11 4014/4885CYP2E1 859/4885PTGS1 3804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.