Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 7/20 | 0.66 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384380 | 0.80 | SCN4A (1.00) | SCN4AMGLLSCN9A | |
| SCHEMBL13168544 | 0.75 | SCN4A (0.75) | SCN4AMGLLSCN9AKDM4ENPC1 | |
| SCHEMBL13978585 | 0.73 | SCN4A (1.00) | SCN4AMGLLSCN9AKDM4ENPC1 | |
| SCHEMBL6775662 | 0.73 | SCN4A (0.77) | SCN4AMGLLSCN9AKDM4ENPC1 | |
| Dimethylformamide SCHEMBL27560975 | 0.73 | SCN4A (0.70) | SCN4AMGLLSCN9AKDM4ENPC1 | |
| SCHEMBL1384902 | 0.72 | SCN4A (1.00) | SCN4ASCN9A | |
| SCHEMBL5649534 | 0.71 | LIPE (0.47) | SCN4AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL1385135 | 0.69 | SCN4A (0.66) | SCN4ASCN9AKDM4EALDH1A1 | |
| SCHEMBL3140335 | 0.69 | MAPT (0.60) | SCN4AMGLLSCN9ANPC1MAPT | |
| SCHEMBL13168524 | 0.67 | SCN4A (0.62) | SCN4AMGLLSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173169-B1 | ARYL SUBSTITUTED PYRAZOLES, IMIDAZOLES, OXAZOLES, THIAZOLES AND PYRROLES, AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2010-05-12 | — | — | EP | claimed |