⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70685 | 0.98 | — | — | |
| SCHEMBL28807956 | 0.95 | MGAM (0.50) | — | |
| SCHEMBL6750259 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL25408509 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL8823685 | 0.95 | — | — | |
| Alcohol SCHEMBL28652002 | 0.93 | MGAM (0.48) | — | |
| SCHEMBL11063668 | 0.93 | — | — | |
| SCHEMBL10836027 | 0.91 | NLRP3 (0.46) | — | |
| SCHEMBL28440518 | 0.91 | MGAM (0.46) | — | |
| SCHEMBL28258298 | 0.89 | MGAM (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781920-B | Process for synthesizing fipronil | KEKI HORMUSJI GHARDA | 2015-05-20 | — | — | CN | disclosed |
| CN-102781920-A | Process for synthesizing fipronil | HORMUSJI GHARDA KEKI | 2012-11-14 | — | — | CN | disclosed |
| US-7842832-B2 | β-amino-α-cyanoacrylates and their use as herbicides | BASF SE (DE) | 2010-11-30 | — | — | US | disclosed |
| EP-1458674-B1 | BETA-AMINO-ALPHA-CYANOACRYLATES AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2010-02-24 | — | — | EP | disclosed |
| CN-100378107-C | Oxazolo-and-furopyrimidines and their use in medicaments against tumors | NOVARTIS AG (CH) | 2008-04-02 | — | — | CN | disclosed |
| US-7294633-B2 | Oxazolo-and furopyrimidines and their use in medicaments against tumors | NOVARTIS AG (CH) | 2007-11-13 | — | — | US | disclosed |
| EP-1390371-B1 | OXAZOLO-AND FUROPYRIMIDINES AND THEIR USE IN MEDICAMENTS AGAINST TUMORS | NOVARTIS AG (CH) | 2006-03-08 | — | — | EP | disclosed |
| US-20050054536-A1 | Reacting an cyanoacrylate compound with amidine compound | BASF SE (DE) | 2005-03-10 | — | — | US | disclosed |
| EP-1458674-A1 | BETA-AMINO-ALPHA-CYANOACRYLATES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-20040152892-A1 | Oxazolo-and furopyrimidines and their use in medicaments against tumors | NOVARTIS AG (CH) | 2004-08-05 | — | — | US | disclosed |
| EP-0131301-A2 | Anorexigenic ergot derivatives | FARMITALIA CARLO ERBA S.p.A. (IT) | 1985-01-16 | — | — | EP | disclosed |
| EP-0129527-A2 | Vulcanisable rubber composition and compounds useful as stabilising agents for rubber vulcanisates | MONSANTO EUROPE S.A./N.V. (BE) | 1984-12-27 | — | — | EP | disclosed |
| EP-0016411-B1 | 5(10- 9)ABEO-ERGOLINE DERIVATIVES, THEIR PREPARATION, AND THERAPEUTIC COMPOSITIONS CONTAINING THEM | FARMITALIA CARLO ERBA S.p.A. (IT) | 1982-09-29 | — | — | EP | disclosed |
| EP-0008802-B1 | ERGOLINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC COMPOSITION CONTAINING THEM | FARMITALIA CARLO ERBA S.p.A. (IT) | 1982-07-21 | — | — | EP | disclosed |
| US-4321381-A | Ergot derivatives | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-03-23 | — | — | US | disclosed |
| US-4317912-A | Tetracyclic indole derivatives | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-03-02 | — | — | US | disclosed |
| US-4252941-A | HYPOTENSIVE AGENTS, ANTIPROLACTINIC AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-24 | — | — | US | disclosed |
| EP-0016411-A2 | 5(10- 9)Abeo-ergoline derivatives, their preparation, and therapeutic compositions containing them | FARMITALIA CARLO ERBA S.p.A. (IT) | 1980-10-01 | — | — | EP | disclosed |
| EP-0008802-A1 | Ergoline derivatives, their preparation and therapeutic composition containing them | FARMITALIA CARLO ERBA S.p.A. (IT) | 1980-03-19 | — | — | EP | disclosed |
| EP-0008802-A1 | Ergoline derivatives, their preparation and therapeutic composition containing them | FARMITALIA CARLO ERBA S.p.A. (IT) | 1980-03-19 | — | — | EP | disclosed |