Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 6/20 | 0.69 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365086 | 0.82 | SCN4A (1.00) | SCN4ASCN9AMAPT | |
| SCHEMBL1384820 | 0.80 | SCN4A (1.00) | SCN4ASCN9A | |
| SCHEMBL13168517 | 0.78 | SCN4A (0.74) | SCN4ASCN9AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3370093 | 0.78 | SCN4A (0.67) | SCN4ASCN9AKDRTEKGAA | |
| SCHEMBL1384902 | 0.76 | SCN4A (1.00) | SCN4ASCN9A | |
| SCHEMBL3367406 | 0.75 | SCN4A (0.79) | SCN4ASCN9AMAPTALDH1A1 | |
| SCHEMBL1386035 | 0.74 | SCN4A (1.00) | SCN4ASCN9A | |
| SCHEMBL13168622 | 0.74 | SCN4A (1.00) | SCN4ASCN9A | |
| SCHEMBL3135653 | 0.74 | IKBKB (0.55) | SCN9ALCKKDRTEKLTA4H | |
| SCHEMBL13168520 | 0.74 | SCN4A (0.77) | SCN4ASCN9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266960-B1 | Aryl-substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles as anticonvulsants | EURO CELTIQUE SA (LU) | 2014-01-22 | — | — | EP | disclosed |
| EP-2266960-A2 | Aryl-substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles as anticonvulsants | EURO-CELTIQUE S.A. (LU) | 2010-12-29 | — | — | EP | disclosed |
| EP-1173169-B1 | ARYL SUBSTITUTED PYRAZOLES, IMIDAZOLES, OXAZOLES, THIAZOLES AND PYRROLES, AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2010-05-12 | — | — | EP | disclosed |
| US-6737418-B2 | CENTRAL NERVOUS SYSTEM DISORDERS; ANTICONVULSANTS | EURO-CELTIQUE S.A. (LU) | 2004-05-18 | — | — | US | disclosed |
| US-6414011-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | EURO-CELTIQUE S.A. (LU) | 2002-07-02 | — | — | US | disclosed |
| CN-1353605-A | Aryl substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles, and use thereof | EURO CELTIQUE SA (LU) | 2002-06-12 | — | — | CN | disclosed |