Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133778 | 0.82 | SCN4A (0.55) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3125837 | 0.77 | SCN9A (0.55) | MAPTMEN1KMT2AL3MBTL1SCN9A | |
| SCHEMBL3129126 | 0.75 | SCN4A (0.57) | IKBKBMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3133736 | 0.74 | MAPT (0.52) | IKBKBMAPTALDH1A1LMNAHPGD | |
| SCHEMBL3370880 | 0.74 | SCN4A (0.69) | IKBKBMAPTALDH1A1GAATNK2 | |
| SCHEMBL3131607 | 0.73 | SCN9A (0.59) | IKBKBMAPTL3MBTL1SCN9A | |
| SCHEMBL3183738 | 0.73 | MAPK8 (0.55) | KDM4EMEN1KMT2A | |
| SCHEMBL3129164 | 0.73 | TLR8 (0.48) | IKBKBMAPTKDM4ESCN9A | |
| SCHEMBL3133858 | 0.73 | SCN9A (0.53) | MAPTL3MBTL1SCN9A | |
| SCHEMBL10944795 | 0.72 | L3MBTL1 (0.56) | MAPTALDH1A1GAAHPGDLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265866-B1 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2010-07-21 | — | — | EP | disclosed |