SCHEMBL3371199

SCHEMBL3371199

O=Cc1ccc(O)c2ccsc12

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.47
ERN1 O75460 9/20 0.40
KDM4E B2RXH2 2/20 0.39
RAB9A P51151 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
HSP90AA1 P07900 1/20 0.39
IDO1 P14902 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TRIM24 O15164 2/20 0.38
TRIM33 Q9UPN9 2/20 0.38
PTGS2 P35354 1/20 0.36
CTSL P07711 1/20 0.36
TYR P14679 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2980034 0.85 CYP2A6 (0.43) CYP2A6ERN1KDM4ERAB9AMEN1
SCHEMBL16048730 0.78 CA1 (0.46) KDM4EMEN1KMT2ACTSLTYR
SCHEMBL16048732 0.78 CA1 (0.46) KDM4EMEN1KMT2ACTSLTYR
SCHEMBL24339585 0.77 CYP2A6 (0.47) CYP2A6KDM4ERAB9AMEN1NPC1
SCHEMBL21625588 0.77 CYP2A6 (0.47) CYP2A6MEN1KMT2A
SCHEMBL11661739 0.77 IDO1 (0.39) IDO1
SCHEMBL5154238 0.76 CYP2A6 (0.40) CYP2A6ERN1PTGS2
SCHEMBL16077423 0.70 TTR (0.50) CTSL
SCHEMBL22122313 0.69 IDO1 (0.33) IDO1
SCHEMBL911722 0.69 NEK1 (0.33) KDM4EIDO1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114437582-A Environment-friendly energy-saving ink cleaning agent and preparation method thereof 南通漫游通艺术包装有限公司 2022-05-06 CN claimed
CN-112457303-B Fluorescent compound and preparation method and application thereof 浙江海洋大学 2022-01-07 CN claimed
CN-112666143-A Fluorescence detection method for alkaline phosphatase activity of environment 浙江海洋大学 2021-04-16 CN claimed
CN-112457303-A Fluorescent compound and preparation method and application thereof 浙江海洋大学 2021-03-09 CN claimed
EP-4665716-A1 CRYSTALLINE FORMS OR SALTS OF A DEUTERATED COMPOUND ALEBUND PHARMACEUTICALS (HONG KONG) LIMITED (HK) 2025-12-24 EP disclosed
CN-118480034-B Crystalline forms or salts of deuterated compounds 礼邦医药(香港)有限公司 2025-02-11 CN disclosed
WO-2024169698-A1 CRYSTALLINE FORMS OR SALTS OF A DEUTERATED COMPOUND ALEBUND PHARMACEUTICALS (HONG KONG) LIMITED (CN) 2024-08-22 WO disclosed
US-20240270731-A1 DEUTERATED COMPOUNDS ALEBUND PHARMACEUTICALS (HONG KONG) LIMITED (CN) 2024-08-15 US disclosed
CN-118480034-A Crystalline forms or salts of deuterated compounds 礼邦医药(香港)有限公司 2024-08-13 CN disclosed
EP-4384507-A1 DEUTERATED COMPOUNDS ALEBUND PHARMACEUTICALS (HONG KONG) LIMITED (HK) 2024-06-19 EP disclosed
CN-116848095-B Deuterated compounds 礼邦生物医药(江苏)有限公司 2024-05-24 CN disclosed
WO-2024005460-A1 COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME 주식회사 트리오어 2024-01-04 WO disclosed
WO-2004041275-A1 SUBSTITUTED 4-ALKOXYOXAZOL DERIVATIVES AS PPAR AGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2004-05-21 WO disclosed
WO-2004020420-A1 NOVEL 2-ARYLTHIAZOLE COMPOUNDS AS PPARALPHA AND PPARGAMA AGONISTS F.HOFFMANN-LA ROCHE AG (CH) 2004-03-11 WO disclosed
EP-1392295-A1 CARBOXYLIC ACID SUBSTITUTED OXAZOLE DERIVATIVES FOR USE AS PPAR-ALPHA AND -GAMMA ACTIVATORS IN THE TREATMENT OF DIABETES F. Hoffmann-La Roche AG (CH) 2004-03-03 EP disclosed
US-6642389-B2 For therapy of diabetes HOFFMANN-LA ROCHE INC. 2003-11-04 US disclosed
US-20030055265-A1 Oxazole derivatives HOFFMANN-LA ROCHE INC. 2003-03-20 US disclosed
WO-2002092084-A1 CARBOXYLIC ACID SUBSTITUTED OXAZOLE DERIVATIVES FOR USE AS PPAR-ALPHA AND -GAMMA ACTIVATORS IN THE TREATMENT OF DIABETES F. HOFFMANN-LA ROCHE AG (CH) 2002-11-21 WO disclosed
WO-1998042691-A1 NEW THIAZOLEDINEDIONES, METHOD FOR THE PRODUCTION THEREOF, AND MEDICAMENTS CONTAINING THE SAME ROCHE DIAGNOSTICS GMBH (DE) 1998-10-01 WO disclosed
WO-1997043284-A1 NEW THIAZOLIDINEDIONES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME BOEHRINGER MANNHEIM GMBH (DE) 1997-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240270731-A1 DEUTERATED COMPOUNDS CYP2D6, CYP11B2, DHCR7 CYP2A6 67/4885ERN1 3833/4885KDM4E 4082/4885
US-20030055265-A1 Oxazole derivatives PPARD, PPARA, PPARG CYP2A6 1435/4885ERN1 2314/4885KDM4E 2767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.