Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1918033 | 0.88 | ALOX5 (0.79) | ALOX5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL245269 | 0.88 | ALOX5 (0.79) | ALOX5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2297349 | 0.88 | ALOX5 (1.00) | ALOX5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3537588 | 0.88 | MEN1 (1.00) | ALOX5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL14710206 | 0.87 | ALOX5 (0.60) | ALOX5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL31485746 | 0.87 | MEN1 (1.00) | ALOX5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10903339 | 0.86 | MEN1 (0.78) | ALOX5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL6118915 | 0.85 | ALOX5 (0.74) | ALOX5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3541369 | 0.84 | ALOX5 (0.76) | ALOX5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3545779 | 0.82 | MEN1 (0.73) | ALOX5MEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003164-A1 | BENZOFURAN DERIVATIVES FOR THE TREATMENT OF HEPATITS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-01-05 | — | — | WO | disclosed |