SCHEMBL3371963

SCHEMBL3371963

C1=CCC(C2(C3CCC3)C=Cc3ccccc32)=C1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 2/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
DRD1 P21728 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
HTR2B P41595 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294617 0.97 CHRM3 (0.30) CHRM3CHRM2CHRM4CHRM5CHRM1
SCHEMBL6294598 0.96 CHRM3 (0.31) CHRM3
SCHEMBL6290097 0.96 CHRM3 (0.31) CHRM3
SCHEMBL3370699 0.77
SCHEMBL8675731 0.72 OXTR (0.30)
SCHEMBL6672401 0.70
SCHEMBL6546834 0.70 OXTR (0.32)
SCHEMBL15265879 0.69 CHRM2 (0.36) CHRM3CHRM2CHRM4CHRM5CHRM1
SCHEMBL8390864 0.69
SCHEMBL6674774 0.68 KDM4E (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1331230-B1 Catalyst composition for preparing olefin polymers IND TECH RES INST (TW) 2010-10-20 EP disclosed
US-6930157-B2 Catalyst composition for preparing olefin polymers INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2005-08-16 US disclosed
US-6875719-B2 Catalyst composition for preparing olefin polymers INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2005-04-05 US disclosed
CN-1171914-C Metallocene compound for preparing olefin polymer and its use 财团法人工业技术研究院 2004-10-20 CN disclosed
US-20030216249-A1 Catalyst composition for preparing olefin polymers INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2003-11-20 US disclosed
US-20030212221-A1 Catalyst composition for preparing olefin polymers INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2003-11-13 US disclosed
EP-1331230-A1 Catalyst composition for preparing olefin polymers INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2003-07-30 EP disclosed
US-20030139284-A1 Catalyst composition for preparing olefin polymers INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2003-07-24 US disclosed
US-20020183195-A1 Catalyst composition for preparing olefin polymers INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2002-12-05 US disclosed
US-20020147104-A1 Catalyst composition for preparing olefin polymers INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2002-10-10 US disclosed
CN-1339507-A Metallocene compound for preparing olefin polymer and its use INIDUSTRIAL TECHNOLOGY INST (CN) 2002-03-13 CN disclosed
EP-1179554-A1 Catalyst composition for preparing olefin polymers INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2002-02-13 EP disclosed