SCHEMBL3372071

SCHEMBL3372071

C=Cc1ccccc1[SiH2]O[SiH2]C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8086300 0.80 ALDH1A1 (0.40) ALDH1A1
SCHEMBL355019 0.77 ALDH1A1 (0.44) ALDH1A1
SCHEMBL21409799 0.77 ALDH1A1 (0.34) ALDH1A1
SCHEMBL6858043 0.76 ALDH1A1 (0.40) ALDH1A1
SCHEMBL23493457 0.76 ALDH1A1 (0.36) ALDH1A1
SCHEMBL5697733 0.76 ALDH1A1 (0.36) ALDH1A1
SCHEMBL23493471 0.76 ALDH1A1 (0.36) ALDH1A1
SCHEMBL5472325 0.76 ALDH1A1 (0.36) ALDH1A1
SCHEMBL28417974 0.72 ALDH1A1 (0.48) ALDH1A1
SCHEMBL4238153 0.71 ALDH1A1 (0.52) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1750157-B1 CONTACT LENS MENICON CO LTD (JP) 2010-10-13 EP disclosed
US-20090247662-A1 Contact Lens Material MATSUMOTO MASAHIRO 2009-10-01 US disclosed
EP-1750157-A1 CONTACT LENS MENICON CO., LTD. (JP) 2007-02-07 EP disclosed
EP-1696257-A1 CONTACT LENS MATERIAL MENICON CO., LTD. (JP) 2006-08-30 EP disclosed