Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 3/20 | 0.35 |
| ▸ | PGK2 | P07205 | 3/20 | 0.35 |
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 2/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.34 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372286 | 0.84 | ACP3 (0.38) | ELANENPSR1ACP3FDPS | |
| SCHEMBL1297880 | 0.81 | ELANE (0.38) | ELANENPSR1NOTUMMAPK1KDM4E | |
| SCHEMBL1297404 | 0.79 | ELANE (0.38) | ELANENPSR1TP53 | |
| SCHEMBL1298373 | 0.78 | ELANE (0.35) | ELANENPSR1ACP3NOTUMFDPS | |
| SCHEMBL1298596 | 0.76 | ELANE (0.41) | ELANENPSR1NOTUMTP53 | |
| SCHEMBL1297947 | 0.76 | ELANE (0.46) | ELANENPSR1TP53 | |
| SCHEMBL12104392 | 0.75 | ELANE (0.36) | ELANENPSR1MAPK1KDM4ETP53 | |
| SCHEMBL1298539 | 0.73 | SIGMAR1 (0.41) | ELANENPSR1MAPK1KDM4ETP53 | |
| SCHEMBL12104407 | 0.71 | SIGMAR1 (0.40) | ELANENPSR1BRD4TP53 | |
| SCHEMBL1297885 | 0.71 | ELANE (0.35) | ELANENPSR1KDM4ECYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010037172-A1 | ANTIOXIDANT COMPOUNDS AND METHODS OF THEIR USE | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2010-04-08 | — | — | WO | disclosed |