SCHEMBL337248

SCHEMBL337248

O=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 1.00
ACLY P53396 2/20 0.37
LMNA P02545 1/20 0.36
CA2 P00918 11/20 0.36
CA1 P00915 10/20 0.36
MMP1 P03956 2/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP8 P22894 2/20 0.36
MMP13 P45452 2/20 0.36
GAA P10253 1/20 0.33
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3368187 1.00 THRB (1.00) THRBACLYLMNACA2CA1
SCHEMBL3368109 1.00 THRB (1.00) THRBACLYLMNACA2CA1
SCHEMBL62447 1.00 THRB (1.00) THRBACLYLMNACA2CA1
SCHEMBL517311 1.00 THRB (1.00) THRBACLYLMNACA2CA1
SCHEMBL2637494 1.00 THRB (1.00) THRBACLYLMNACA2CA1
SCHEMBL3628434 1.00 THRB (1.00) THRBACLYLMNACA2CA1
SCHEMBL25223581 1.00 THRB (1.00) THRBACLYLMNACA2CA1
SCHEMBL2106472 1.00 THRB (1.00) THRBACLYLMNACA2CA1
SCHEMBL24715 1.00 THRB (1.00) THRBACLYLMNACA2CA1
SCHEMBL20657170 1.00 THRB (1.00) THRBACLYLMNACA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600827-B2 Method for the synthesis of a two-dimensional or quasi-two-dimensional polymer film, the two-dimensional or quasi-two-dimensional polymer film and the use MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-04-14 US claimed
US-20250339598-A1 EXTRACORPOREAL OXYGENATION DEVICE BOUNDLESS SCIENCE INCORPORATED (US) 2025-11-06 US claimed
WO-2025127926-A1 METHOD FOR REMOVING PER- AND POLYFLUOROALKYL SUBSTANCES (PFAS) FROM AN AQUEOUS STREAM, DEVICE, AND SYSTEM FOR REMOVING SAID PFAS FERR TECH HOLDING B.V. (NL) 2025-06-19 WO claimed
CN-120084927-A Method for detecting various perfluorinated compounds in water environment 昆明理工大学 2025-06-03 CN claimed
WO-2025061960-A1 PROCESS FOR THE PURIFICATION OF PERFLUOROALKYL ACIDS CHIRON AS (NO) 2025-03-27 WO claimed
EP-4527829-A1 PROCESS FOR THE PURIFICATION OF PERFLUOROALKYL ACIDS Chiron AS (NO) 2025-03-26 EP claimed
WO-2025049798-A1 SYSTEMS, METHODS, AND DEVICES FOR DESTRUCTION OF PER- AND POLYFLUOROALKYL SUBSTANCES (PFAS) AND FOR REACTIVATING SPENT ACTIVATED CARBON 6K INC. (US) 2025-03-06 WO claimed
CN-119000959-B Method for detecting perfluorinated compounds and hexabromocyclododecane compounds in orthodontic transparent appliance 广州医科大学附属口腔医院(广州医科大学羊城医院) 2025-01-17 CN claimed
CN-119000959-A Method for detecting perfluorinated compounds and hexabromocyclododecane compounds in orthodontic transparent appliance 广州医科大学附属口腔医院(广州医科大学羊城医院) 2024-11-22 CN claimed
CN-114651030-B Two-dimensional or quasi-two-dimensional polymer film synthesis method, two-dimensional or quasi-two-dimensional polymer film and application thereof 德累斯顿工业技术大学 2024-10-18 CN claimed
WO-2021028429-A1 METHOD FOR THE SYNTHESIS OF A TWO-DIMENSIONAL OR QUASI-TWO-DIMENSIONAL POLYMER FILM, THE TWO-DIMENSIONAL OR QUASI-TWO-DIMENSIONAL POLYMER FILM AND THE USE Technische Universität Dresden (DE) 2021-02-18 WO claimed
EP-3778711-A1 METHOD FOR THE SYNTHESIS OF A TWO-DIMENSIONAL OR QUASI-TWO-DIMENSIONAL POLYMER FILM, THE TWO-DIMENSIONAL OR QUASI-TWO-DIMENSIONAL POLYMER FILM AND THE USE Technische Universität Dresden (DE) 2021-02-17 EP claimed
CN-112229935-A Analysis and detection method of perfluorinated compounds 南京市产品质量监督检验院 2021-01-15 CN claimed
US-20200197307-A1 ULTRASOUND-SENSITIVE PEPTIDE PARTICLES FOR SPATIALLY RESOLVED MOLECULE DELIVERY THE PENN STATE RESEARCH FOUNDATION 2020-06-25 US claimed
US-20200179909-A1 SYNTHESIS AND IMMOBILIZATION OF A FERROUS SULFITE CATALYST AND METHOD OF DEGRADING FLUORINATED ORGANIC CHEMICALS IN AQUEOUS MEDIA THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S. ENVIRONMENTAL PROTECTION AGENCY 2020-06-11 US claimed
CN-111100731-A Lubricating grease and preparation method thereof 中国石油化工股份有限公司 2020-05-05 CN claimed
CN-111100724-A Perfluoropolyether lubricating grease and preparation method thereof 中国石油化工股份有限公司 2020-05-05 CN claimed
CN-111040990-A Construction method and application of zebra fish embryo perfluorinated compound internal exposure model 深圳先进技术研究院 2020-04-21 CN claimed
CN-110715999-A High-throughput screening method for 200 chemical risk substances in toy 中国检验检疫科学研究院 2020-01-21 CN claimed
WO-2012024592-A2 COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING FLUOROUS-SOLUBLE POLYMERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-02-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600827-B2 Method for the synthesis of a two-dimensional or quasi-two-dimensional polymer film, the two-dimensional or quasi-two-dimensional polymer film and the use PUF60, PARG, EED THRB 2225/4885ACLY 3242/4885LMNA 1681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.