Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375660 | 1.00 | REN (0.62) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3372672 | 0.92 | REN (0.64) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3372166 | 0.92 | REN (0.74) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL5614698 | 0.92 | REN (0.74) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3375776 | 0.92 | REN (0.74) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3372209 | 0.90 | REN (0.59) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3372203 | 0.90 | REN (0.59) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3374973 | 0.89 | REN (0.57) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3374970 | 0.89 | REN (0.57) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3373295 | 0.87 | REN (0.67) | RENHTR1AADRA1DHTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108570069-A | The method for being used to prepare three [3- (alkoxysilyl) propyl] isocyanuric acid esters | 赢创德固赛有限公司 | 2018-09-25 | — | — | CN | claimed |
| CN-108570070-A | The method for being used to prepare three [3- (alkoxysilyl) propyl] isocyanuric acid esters | 赢创德固赛有限公司 | 2018-09-25 | — | — | CN | claimed |
| EP-2486005-B1 | PYRROLIDINE GPR40 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2014-06-18 | — | — | EP | claimed |
| CN-103435817-A | Method for directly extracting lignin in process of using corn bran to prepare low-molecular-weight mixed ether | HUBEI PROFESSIONAL NEW BIOLOG MATERIAL CO LTD | 2013-12-11 | — | — | CN | claimed |
| WO-2013171755-A2 | \"COMBUSTION SYNTHESIS OF NANOCRYSTALLINE ALKALI AND ALKALINE EARTH METAL OXIDES OR MIXTURE THEREOF AND ITS APPLICATIONS IN SYNTHESIS OF [4- (ALKYL/ARYL)-OXY- 1,3 -DIOXOLANE-2- ONE] AND 2-OXAZOLIDINONES\ | YADAV GANAPATI DADASAHEB (IN) | 2013-11-21 | — | — | WO | claimed |
| EP-1863477-B1 | 3,4-SUBSTITUTED PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF HYPERTENSION | NOVARTIS AG (CH) | 2010-11-03 | — | — | EP | claimed |
| US-7807709-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-10-05 | — | — | US | claimed |
| US-20080194549-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | claimed |
| EP-0443861-B2 | Organic electroluminescence device | SUMITOMO CHEMICAL CO (JP) | 2008-05-28 | — | — | EP | claimed |
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | claimed |
| EP-0832082-B1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ASTRAZENECA AB (SE) | 2001-11-21 | — | — | EP | claimed |
| EP-0516392-B1 | Naphthyridine derivatives as angiotensin II inhibitors | ASTRAZENECA AB (SE) | 2001-08-29 | — | — | EP | claimed |
| EP-0443861-B1 | Organic electroluminescence device | SUMITOMO CHEMICAL CO (JP) | 1995-07-05 | — | — | EP | claimed |
| EP-0583396-B1 | ACID STABLE GEL STICK ANTIPERSPIRANT COMPOSITIONS AND PROCESS FOR MAKING THEM | PROCTER & GAMBLE (US) | 1995-01-25 | — | — | EP | claimed |
| EP-0267778-B1 | AZOLE DERIVATIVES USEFUL IN CONTROLLING PLANT DISEASES AND REGULATING PLANT GROWTH | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-03-24 | — | — | EP | claimed |
| EP-0232937-B1 | ANTI-HISTAMINIC COMPOSITIONS CONTAINING N-HETEROCYCLYL-4-PIPERIDINAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-08-19 | — | — | EP | claimed |
| EP-0085291-B1 | 2-OXO-1-(AMINOCARBONYLAMINOSULFONYLAMINOCARBONYL)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1988-08-17 | — | — | EP | claimed |
| CN-108570070-A | The method for being used to prepare three [3- (alkoxysilyl) propyl] isocyanuric acid esters | 赢创德固赛有限公司 | 2018-09-25 | — | — | CN | disclosed |
| US-4262129-A | Preparation of a 3-thienylmalonic acid and the corresponding diesters | OCE-ANDENO B.V. (NL) | 1981-04-14 | — | — | US | disclosed |
| EP-0002846-A1 | 3-Thienylmalonic acids, the corresponding diesters and their preparation | Océ-Andeno B.V. (NL) | 1979-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194549-A1 | Organic Compounds | REN, ACE, OTC | REN 1/4885HTR1A 2156/4885ADRA1D 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.