SCHEMBL3373066

SCHEMBL3373066

CC(C)N1CCC(NC(=O)Oc2nc3c(C(=O)N4CCOCC4)cccc3n2CC(=O)Nc2ccc(Cl)cn2)CC1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 18/20 0.55
F2 P00734 2/20 0.55
MOK Q9UQ07 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3371161 0.97 F10 (0.53) F10F2MOK
SCHEMBL3374319 0.92 F10 (0.55) F10F2
SCHEMBL3372878 0.91 F10 (0.56) F10F2
SCHEMBL1378777 0.89 F10 (0.61) F10F2
SCHEMBL3369266 0.88 F10 (0.55) F10F2
SCHEMBL1380230 0.86 F10 (0.58) F10F2
SCHEMBL3372792 0.86 F10 (0.49) F10F2
SCHEMBL3371486 0.85 F10 (0.60) F10F2
SCHEMBL3369023 0.84 F10 (0.58) F10F2
SCHEMBL3368811 0.83 F10 (0.51) F10F2MOK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636216-B1 BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI AVENTIS DEUTSCHLAND (DE) 2010-07-21 EP claimed