Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231945 | 0.89 | F10 (0.55) | F10F2HRH3 | |
| SCHEMBL1381845 | 0.89 | F10 (0.56) | F10F2HRH3KMT2A | |
| SCHEMBL3369704 | 0.89 | F10 (0.54) | F10F2 | |
| SCHEMBL3371161 | 0.86 | F10 (0.53) | F10F2MOK | |
| SCHEMBL3372792 | 0.86 | F10 (0.49) | F10F2HRH3 | |
| SCHEMBL4416638 | 0.85 | F10 (0.47) | F10F2HRH3LRRK2 | |
| SCHEMBL1652749 | 0.84 | F10 (0.69) | F10F2 | |
| SCHEMBL6016992 | 0.84 | F10 (0.46) | F10F2HRH3KMT2AMOK | |
| SCHEMBL3368978 | 0.84 | F10 (0.54) | F10F2 | |
| SCHEMBL3373066 | 0.83 | F10 (0.55) | F10F2MOK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-B1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-07-21 | — | — | EP | claimed |