Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 12/20 | 0.53 |
| ▸ | POLG | P54098 | 2/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100853 | 0.87 | P2RY2 (0.51) | P2RY2POLGP2RY4P2RY6LMNA | |
| SCHEMBL3100892 | 0.87 | P2RY2 (0.51) | P2RY2POLGP2RY4P2RY6LMNA | |
| SCHEMBL11330336 | 0.85 | LMNA (0.62) | P2RY2POLGP2RY4P2RY6LMNA | |
| SCHEMBL3100908 | 0.85 | LMNA (0.49) | P2RY2POLGP2RY4P2RY6LMNA | |
| SCHEMBL3100871 | 0.85 | LMNA (0.49) | P2RY2POLGP2RY4P2RY6LMNA | |
| SCHEMBL8506608 | 0.84 | P2RY2 (0.67) | P2RY2POLGP2RY4P2RY6 | |
| SCHEMBL1153021 | 0.83 | P2RY2 (0.56) | P2RY2POLGP2RY4P2RY6LMNA | |
| SCHEMBL2537576 | 0.83 | LMNA (0.64) | P2RY2POLGP2RY4P2RY6LMNA | |
| SCHEMBL11327207 | 0.83 | LMNA (0.64) | P2RY2POLGP2RY4P2RY6LMNA | |
| SCHEMBL18438956 | 0.83 | P2RY2 (0.57) | P2RY2POLGP2RY4P2RY6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114224852-A | Azacitidine freeze-dried preparation for injection | 鲁南制药集团股份有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-114129523-A | Azacitidine freeze-dried preparation for injection | 鲁南制药集团股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-108451901-B | Azacitidine preparation and preparation method thereof | 青岛市中心医院 | 2020-07-17 | — | — | CN | disclosed |
| US-20100055047-A1 | Methods for treating bronchial premalignancy and lung cancer | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2010-03-04 | — | — | US | disclosed |