Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372850 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 | |
| SCHEMBL3376673 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 | |
| SCHEMBL13042286 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 | |
| SCHEMBL16869374 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 | |
| SCHEMBL10445605 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 | |
| SCHEMBL1989989 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 | |
| SCHEMBL1142285 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 | |
| SCHEMBL1142491 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 | |
| SCHEMBL21357426 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 | |
| SCHEMBL3371335 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201156-A2 | BIOFUEL COMPOSITION AND MANUFACTURING PROCESS | Busch, Rainer (US) | 2010-06-30 | — | — | EP | claimed |
| WO-2009035689-A2 | BIOFUEL COMPOSITION AND MANUFACTURING PROCESS | BUSCH RAINER (US) | 2009-03-19 | — | — | WO | claimed |
| US-20170135962-A1 | NOVEL DIESTER AND TRIESTER BASED LOW MOLECULAR WEIGHT, BIODEGRADEABLE CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | SIRNA THERAPEUTICS, INC. (US) | 2017-05-18 | — | — | US | disclosed |
| US-9402816-B2 | Diester and triester based low molecular weight, biodegradeable cationic lipids for oligonucleotide delivery | SIMA THERAPEUTICS, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150133519-A1 | NOVEL DIESTER AND TRIESTER BASED LOW MOLECULAR WEIGHT, BIODEGRADEABLE CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | BANK OF AMERICA, N.A. | 2015-05-14 | — | — | US | disclosed |
| EP-2201156-A2 | BIOFUEL COMPOSITION AND MANUFACTURING PROCESS | Busch, Rainer (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009035689-A2 | BIOFUEL COMPOSITION AND MANUFACTURING PROCESS | BUSCH RAINER (US) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133519-A1 | NOVEL DIESTER AND TRIESTER BASED LOW MOLECULAR WEIGHT, BIODEGRADEABLE CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | CYP46A1, CETP, LIPC | LPAR3 52/4885LPAR2 105/4885LPAR1 82/4885 |
| US-20170135962-A1 | NOVEL DIESTER AND TRIESTER BASED LOW MOLECULAR WEIGHT, BIODEGRADEABLE CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | CYP46A1, CETP, LIPC | LPAR3 52/4885LPAR2 105/4885LPAR1 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.